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sugarless gum
Sugarless gum provides mechanical stimulation to oral tissues and may promote saliva production without contributing to dental caries.
Sugarless gum provides mechanical stimulation to oral tissues and may promote saliva production without contributing to dental caries. Used for Dental caries prevention, Xerostomia (dry mouth) symptom relief.
At a glance
| Generic name | sugarless gum |
|---|---|
| Also known as | Samara Gum |
| Sponsor | Kasr El Aini Hospital |
| Modality | Biologic |
| Therapeutic area | Dental/Oral Health |
| Phase | FDA-approved |
Mechanism of action
Sugarless gum is a non-pharmaceutical confectionery product that stimulates mastication and salivary flow. The increased saliva can help neutralize acids and reduce plaque formation. It is formulated with sugar substitutes (such as xylitol, sorbitol, or aspartame) rather than sucrose to avoid promoting tooth decay.
Approved indications
- Dental caries prevention
- Xerostomia (dry mouth) symptom relief
Common side effects
- Gastrointestinal distress (from sugar alcohols)
- Jaw discomfort
Key clinical trials
- Effect of Chewing Different Flavor Gum on Procedural Pain and Fear (NA)
- Effects of Chewing Gum for Dry Mouth in Diabetes (NA)
- Preoperative Chewing Gum on Anxiety and Postoperative Nausea and Vomiting, Gastrointestinal Function (NA)
- Effect of Chewing Gum and WeChat Enhanced Instructions on the Bowel Preparation Quality in Patients With Constipation (NA)
- Chewing Gum on Postoperative Ileus in Children (NA)
- Effectiveness of Gum Chewing on Polyethylene Glycol Related Intake Adherence, GI Side Effects and Bowel Preparation (NA)
- Healthy Adult Male Facial Skin Surface Lipid Pheromone p.o. to Treat Opioid Addiction (PHASE3)
- The Effectiveness of Chewing Gum in Influencing Capsule Endoscopy Transit Time (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- sugarless gum CI brief — competitive landscape report
- sugarless gum updates RSS · CI watch RSS
- Kasr El Aini Hospital portfolio CI