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succinylated gelatin injection
Succinylated gelatin acts as a plasma volume expander by increasing colloid osmotic pressure to restore intravascular fluid volume.
Succinylated gelatin acts as a plasma volume expander by increasing colloid osmotic pressure to restore intravascular fluid volume. Used for Hypovolemia and shock requiring fluid resuscitation, Perioperative volume replacement during surgery.
At a glance
| Generic name | succinylated gelatin injection |
|---|---|
| Sponsor | Nanjing Chia-tai Tianqing Pharmaceutical |
| Drug class | Colloid plasma volume expander |
| Modality | Small molecule |
| Therapeutic area | Critical Care / Anesthesia |
| Phase | FDA-approved |
Mechanism of action
Succinylated gelatin is a modified gelatin derivative that functions as a colloid-based volume replacement agent. When administered intravenously, it increases plasma oncotic pressure, drawing fluid into the intravascular space and expanding circulating blood volume. This helps restore hemodynamic stability and tissue perfusion in hypovolemic states.
Approved indications
- Hypovolemia and shock requiring fluid resuscitation
- Perioperative volume replacement during surgery
Common side effects
- Allergic reactions
- Hyperamylasemia
- Coagulopathy
- Acute kidney injury
Key clinical trials
- Clinical Study on the Effectiveness and Safety of Succinylated Gelatin Injection (NA)
- Clinical Study on the Effectiveness and Safety of Succinylated Gelatin Electrolyte Sodium Acetate Injection (NA)
- R0 Resection Rate Between CSP, cEMR and hEMR for 1-2 cm Colorectal SSLs (NA)
- Tranexamic Acid During Upper GI Endoscopic Resection Procedures (PHASE4)
- Study of Albumin to Reduce Inflammation Following Surgery (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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