Last reviewed 2026-04-20 · How we verify

SUCCIMER

At a glance

Approved indications

No approved indications tracked.

Common side effects

• Nausea, vomiting, diarrhea, appetite loss, hemorrhoidal symptoms, metallic taste in mouth
• Back pain, abdominal cramps, stomach pains, head pain, rib pain, chills, flank pain, fever, flu-like symptoms, heavy head/tired, head cold, headache, moniliasis
• Elevated ALT or AST, alkaline phosphatase, serum cholesterol
• Sore throat, rhinorrhea, nasal congestion, cough
• Papular rash, herpetic rash, rash, mucocutaneous eruptions, pruritis
• Drowsiness, dizziness, sensorimotor neuropathy, sleepiness, paresthesia
• Cloudy film in eye, ears plugged, otitis media, eyes watery
• Neutropenia, increased platelet count, eosinophilia

Drug interactions

• Laboratory Tests
• Other Chelation Therapies (e.g., CaNa2EDTA)

Key clinical trials

• Edetate Calcium Disodium or Succimer in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Chemotherapy (PHASE1)
• Monitoring, Detoxifying, and Rebalancing Metals During Acute Myeloid Leukemia (AML) Therapy, a Phase 2 Randomized Study (PHASE2)
• Electrophysiological Study of the Functioning of Magnocellular Visual Pathway in Regular Cannabis Users (NA)
• The Individual Therapy for Patients With Wilson's Disease (EARLY_PHASE1)
• Treatment of Lead-Exposed Children Trial (PHASE3)
• Mercury Chelation to Treat Autism (PHASE2)
• Dimercaptosuccinic Acid (DMSA) Treatment of Children With Autism and Heavy Metal Toxicity (PHASE1, PHASE2)
• The Combined Effect of 2,3-Dimercaptosuccinic Acid and Multi-Nutrients on Children in Lead Poisoning

Primary sources

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