FDA authorised Suboxone on 30 August 2010 · 22,075 US adverse-event reports
Marketing authorisations
FDA — authorised 30 August 2010
Application: NDA022410
Marketing authorisation holder: INDIVIOR
Status: supplemented
FDA
Status: approved
Safety signals — FAERS
Adverse reaction reports describe suspected side effects. A report does not mean the drug caused the event — co-medications, underlying disease and coincidence all contribute.
Window: 20 April 2025 – 20 April 2026
Total reports: 22,075
Most-reported reactions
Drug Dependence — 4,368 reports (19.79%)
Drug Withdrawal Syndrome — 3,610 reports (16.35%)
Pain — 2,647 reports (11.99%)
Off Label Use — 2,186 reports (9.9%)
Overdose — 1,887 reports (8.55%)
Nausea — 1,753 reports (7.94%)
Emotional Distress — 1,473 reports (6.67%)
Vomiting — 1,467 reports (6.65%)
Anxiety — 1,429 reports (6.47%)
Foetal Exposure During Pregnancy — 1,255 reports (5.69%)