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Subcutaneous injection of Secukinumab

Peking Union Medical College · FDA-approved active Small molecule

Subcutaneous injection of Secukinumab is a IL-17A inhibitor (monoclonal antibody) Small molecule drug developed by Peking Union Medical College. It is currently FDA-approved for Moderate to severe plaque psoriasis, Psoriatic arthritis, Ankylosing spondylitis.

Secukinumab is a monoclonal antibody that blocks interleukin-17A (IL-17A), a key inflammatory cytokine involved in immune-mediated diseases.

Secukinumab is a monoclonal antibody that blocks interleukin-17A (IL-17A), a key inflammatory cytokine involved in immune-mediated diseases. Used for Moderate to severe plaque psoriasis, Psoriatic arthritis, Ankylosing spondylitis.

At a glance

Generic nameSubcutaneous injection of Secukinumab
SponsorPeking Union Medical College
Drug classIL-17A inhibitor (monoclonal antibody)
TargetIL-17A (Interleukin-17A)
ModalitySmall molecule
Therapeutic areaImmunology
PhaseFDA-approved

Mechanism of action

Secukinumab selectively binds to and neutralizes IL-17A, preventing its interaction with IL-17 receptors on immune and tissue cells. This inhibition reduces the recruitment and activation of neutrophils and other inflammatory cells, thereby suppressing the inflammatory cascade underlying autoimmune and inflammatory conditions. By targeting IL-17A specifically, it modulates the Th17 immune response without broadly suppressing the entire immune system.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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Frequently asked questions about Subcutaneous injection of Secukinumab

What is Subcutaneous injection of Secukinumab?

Subcutaneous injection of Secukinumab is a IL-17A inhibitor (monoclonal antibody) drug developed by Peking Union Medical College, indicated for Moderate to severe plaque psoriasis, Psoriatic arthritis, Ankylosing spondylitis.

How does Subcutaneous injection of Secukinumab work?

Secukinumab is a monoclonal antibody that blocks interleukin-17A (IL-17A), a key inflammatory cytokine involved in immune-mediated diseases.

What is Subcutaneous injection of Secukinumab used for?

Subcutaneous injection of Secukinumab is indicated for Moderate to severe plaque psoriasis, Psoriatic arthritis, Ankylosing spondylitis, Non-radiographic axial spondyloarthritis.

Who makes Subcutaneous injection of Secukinumab?

Subcutaneous injection of Secukinumab is developed and marketed by Peking Union Medical College (see full Peking Union Medical College pipeline at /company/peking-union-medical-college).

What drug class is Subcutaneous injection of Secukinumab in?

Subcutaneous injection of Secukinumab belongs to the IL-17A inhibitor (monoclonal antibody) class. See all IL-17A inhibitor (monoclonal antibody) drugs at /class/il-17a-inhibitor-monoclonal-antibody.

What development phase is Subcutaneous injection of Secukinumab in?

Subcutaneous injection of Secukinumab is FDA-approved (marketed).

What are the side effects of Subcutaneous injection of Secukinumab?

Common side effects of Subcutaneous injection of Secukinumab include Nasopharyngitis, Upper respiratory tract infection, Diarrhea, Headache, Injection site reactions.

What does Subcutaneous injection of Secukinumab target?

Subcutaneous injection of Secukinumab targets IL-17A (Interleukin-17A) and is a IL-17A inhibitor (monoclonal antibody).

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