Last reviewed · How we verify

STW 5-II

Universitaire Ziekenhuizen KU Leuven · FDA-approved active Small molecule ✓ Verified May 2026

STW 5-II is a Herbal combination product Small molecule drug developed by Universitaire Ziekenhuizen KU Leuven. It is currently FDA-approved for Functional dyspepsia, Irritable bowel syndrome.

STW 5-II is a herbal combination product that modulates gastrointestinal motility and secretion to relieve functional gastrointestinal symptoms.

STW 5-II is a treatment being studied for Functional Dyspepsia, a type of Functional Gastrointestinal Disorder. It is being compared to a placebo in a clinical trial to assess its effects on duodenal mucosa and symptoms in patients with Functional Dyspepsia.

At a glance

Generic nameSTW 5-II
SponsorUniversitaire Ziekenhuizen KU Leuven
Drug classHerbal combination product
ModalitySmall molecule
Therapeutic areaGastroenterology
PhaseFDA-approved

Mechanism of action

STW 5-II contains a standardized extract of nine medicinal plants that work synergistically to improve gastric emptying, reduce visceral pain, and normalize intestinal secretion. The formulation addresses multiple pathophysiological mechanisms underlying functional dyspepsia and irritable bowel syndrome through its spasmolytic, prokinetic, and anti-inflammatory properties.

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Frequently asked questions about STW 5-II

What is STW 5-II?

STW 5-II is a Herbal combination product drug developed by Universitaire Ziekenhuizen KU Leuven, indicated for Functional dyspepsia, Irritable bowel syndrome.

How does STW 5-II work?

STW 5-II is a herbal combination product that modulates gastrointestinal motility and secretion to relieve functional gastrointestinal symptoms.

What is STW 5-II used for?

STW 5-II is indicated for Functional dyspepsia, Irritable bowel syndrome.

Who makes STW 5-II?

STW 5-II is developed and marketed by Universitaire Ziekenhuizen KU Leuven (see full Universitaire Ziekenhuizen KU Leuven pipeline at /company/universitaire-ziekenhuizen-ku-leuven).

What drug class is STW 5-II in?

STW 5-II belongs to the Herbal combination product class. See all Herbal combination product drugs at /class/herbal-combination-product.

What development phase is STW 5-II in?

STW 5-II is FDA-approved (marketed).

What are the side effects of STW 5-II?

Common side effects of STW 5-II include Gastrointestinal disturbances, Allergic reactions.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing