Last reviewed 2026-04-23 · How we verify

Steroid Taper

Steroid Taper works by gradually reducing the body's levels of steroids to allow the adrenal glands to resume normal function.

Steroid Taper works by gradually reducing the body's levels of steroids to allow the adrenal glands to resume normal function. Used for Treatment of Cushing's syndrome.

At a glance

Mechanism of action

This process helps to minimize withdrawal symptoms and allows the body to adapt to the decrease in steroid levels. Steroid Taper is typically used to treat patients who have been taking steroids for an extended period and need to gradually reduce their dosage.

Approved indications

• Treatment of Cushing's syndrome

Common side effects

• Nausea
• Headache
• Fatigue
• Dizziness
• Insomnia

Key clinical trials

• Loteprednol Etabonate Versus Prednisolone Acetate for Anterior Chamber Granulomas (PHASE4)
• Gene Replacement Therapy for Treatment of Paediatric Patients With CTNNB1 Neurodevelopmental Syndrome (PHASE1, PHASE2)
• Ruxolitinib, Human Chorionic Gonadotropin (uhCG/EGF), and Dose De-escalated Corticosteroids (PHASE1, PHASE2)
• MAGIC Ruxolitinib for aGVHD (PHASE2)
• Inhaled Budesonide for REcurrence Prevention and Adjuvant THerapy in Checkpoint Inhibitor Pneumonitis (PHASE2)
• LBL-2016 for Children or Adolescents in China (PHASE3)
• Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or Dysregulation (PHASE2)
• A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation (PHASE2)

Primary sources

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