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Sterile Sodium Chloride

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · FDA-approved active Small molecule

Sterile Sodium Chloride is a Electrolyte replacement / Crystalloid fluid Small molecule drug developed by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). It is currently FDA-approved for Fluid and electrolyte replacement in dehydration, Maintenance of fluid and electrolyte balance during surgery or critical illness, Vehicle for intravenous medication administration. Also known as: 0.9% Sodium Chloride Water for Injection.

Sterile sodium chloride is an isotonic saline solution that restores and maintains electrolyte balance and fluid volume in the body.

Sterile sodium chloride is an isotonic saline solution that restores and maintains electrolyte balance and fluid volume in the body. Used for Fluid and electrolyte replacement in dehydration, Maintenance of fluid and electrolyte balance during surgery or critical illness, Vehicle for intravenous medication administration.

At a glance

Generic nameSterile Sodium Chloride
Also known as0.9% Sodium Chloride Water for Injection
SponsorNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Drug classElectrolyte replacement / Crystalloid fluid
ModalitySmall molecule
Therapeutic areaGeneral medicine / Supportive care
PhaseFDA-approved

Mechanism of action

Sodium chloride is an essential electrolyte that regulates osmotic pressure, maintains cellular hydration, and supports nerve and muscle function. As a sterile injectable solution, it is used to replace lost fluids and electrolytes, restore blood volume, and serve as a vehicle for administering other medications. It works by providing physiologically balanced concentrations of sodium and chloride ions.

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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Frequently asked questions about Sterile Sodium Chloride

What is Sterile Sodium Chloride?

Sterile Sodium Chloride is a Electrolyte replacement / Crystalloid fluid drug developed by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), indicated for Fluid and electrolyte replacement in dehydration, Maintenance of fluid and electrolyte balance during surgery or critical illness, Vehicle for intravenous medication administration.

How does Sterile Sodium Chloride work?

Sterile sodium chloride is an isotonic saline solution that restores and maintains electrolyte balance and fluid volume in the body.

What is Sterile Sodium Chloride used for?

Sterile Sodium Chloride is indicated for Fluid and electrolyte replacement in dehydration, Maintenance of fluid and electrolyte balance during surgery or critical illness, Vehicle for intravenous medication administration.

Who makes Sterile Sodium Chloride?

Sterile Sodium Chloride is developed and marketed by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (see full National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) pipeline at /company/national-institute-of-diabetes-and-digestive-and-kidney-diseases-niddk).

Is Sterile Sodium Chloride also known as anything else?

Sterile Sodium Chloride is also known as 0.9% Sodium Chloride Water for Injection.

What drug class is Sterile Sodium Chloride in?

Sterile Sodium Chloride belongs to the Electrolyte replacement / Crystalloid fluid class. See all Electrolyte replacement / Crystalloid fluid drugs at /class/electrolyte-replacement-crystalloid-fluid.

What development phase is Sterile Sodium Chloride in?

Sterile Sodium Chloride is FDA-approved (marketed).

What are the side effects of Sterile Sodium Chloride?

Common side effects of Sterile Sodium Chloride include Hypernatremia (elevated sodium levels), Fluid overload / pulmonary edema, Phlebitis at injection site, Hypokalemia (low potassium).

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