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Standard of Care Treatment
Standard of Care Treatment is a PD-1 inhibitor Small molecule drug developed by Janssen Research & Development, LLC. It is currently in Phase 3 development for Non-small cell lung cancer, PD-L1 positive, Head and neck squamous cell carcinoma, Urothelial carcinoma. Also known as: cytoxan.
This drug works by inhibiting the PD-1 receptor, which helps the immune system recognize and attack cancer cells.
This drug works by inhibiting the PD-1 receptor, which helps the immune system recognize and attack cancer cells. Used for Non-small cell lung cancer, PD-L1 positive, Head and neck squamous cell carcinoma, Urothelial carcinoma.
At a glance
| Generic name | Standard of Care Treatment |
|---|---|
| Also known as | cytoxan |
| Sponsor | Janssen Research & Development, LLC |
| Drug class | PD-1 inhibitor |
| Target | PD-1 |
| Modality | Small molecule |
| Therapeutic area | Oncology |
| Phase | Phase 3 |
Mechanism of action
By blocking the PD-1 receptor, the drug allows the immune system to function more effectively, leading to the destruction of cancer cells. This mechanism is often referred to as immunotherapy. The drug's ability to inhibit the PD-1 receptor is key to its therapeutic effects.
Approved indications
- Non-small cell lung cancer, PD-L1 positive
- Head and neck squamous cell carcinoma
- Urothelial carcinoma
- Melanoma
- Renal cell carcinoma
- Colorectal cancer
- Gastric cancer
- Esophageal cancer
- Cervical cancer
- Hepatocellular carcinoma
Common side effects
- Pneumonitis
- Hypothyroidism
- Hyperthyroidism
- Diarrhea
- Fatigue
- Nausea
- Rash
- Pruritus
- Arthralgia
- Myalgia
Key clinical trials
- A Study of Targeted Radiation Therapy in People With Non-Small Cell Lung Cancer (NSCLC) (PHASE2)
- Parent Study Name: Pulmonary Rehabilitation to Reduce Post-Tuberculosis Morbidity (TB Pure) (NA)
- A Study of Weight Loss Intervention With Tirzepatide and Progestin Intrauterine Device to Treat Endometrial Hyperplasia and Grade 1 Endometrial Cancer (PHASE2)
- Topical Methylene Blue-Photodynamic Therapy (MB-PDT) for Burn Wound Infection (PHASE1, PHASE2)
- Effect of Anticoagulant Therapy on Endometrial Receptivity and Pregnancy Outcomes in Infertility
- A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer (PHASE2)
- Shared Decision-Making Decision Aid for Newly Diagnosed Breast Cancer : A Multi-Center Randomized Controlled Trial (NA)
- Study of a Support Program for Quality of Life in Chinese Cancer Patients and Survivors (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Standard of Care Treatment CI brief — competitive landscape report
- Standard of Care Treatment updates RSS · CI watch RSS
- Janssen Research & Development, LLC portfolio CI
Frequently asked questions about Standard of Care Treatment
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Related
- Drug class: All PD-1 inhibitor drugs
- Target: All drugs targeting PD-1
- Manufacturer: Janssen Research & Development, LLC — full pipeline
- Therapeutic area: All drugs in Oncology
- Indication: Drugs for Non-small cell lung cancer, PD-L1 positive
- Indication: Drugs for Head and neck squamous cell carcinoma
- Indication: Drugs for Urothelial carcinoma
- Also known as: cytoxan
- Compare: Standard of Care Treatment vs similar drugs
- Pricing: Standard of Care Treatment cost, discount & access