Last reviewed · How we verify
Standard of Care Preoperative antibiotics
Standard of Care Preoperative antibiotics is a Prophylactic antibiotic regimen Small molecule drug developed by The George Washington University Biostatistics Center. It is currently in Phase 3 development for Surgical site infection prevention in elective surgical procedures.
Standard preoperative antibiotics prevent surgical site infections by eliminating or reducing bacterial colonization at the operative site before incision.
Standard preoperative antibiotics prevent surgical site infections by eliminating or reducing bacterial colonization at the operative site before incision. Used for Surgical site infection prevention in elective surgical procedures.
At a glance
| Generic name | Standard of Care Preoperative antibiotics |
|---|---|
| Sponsor | The George Washington University Biostatistics Center |
| Drug class | Prophylactic antibiotic regimen |
| Modality | Small molecule |
| Therapeutic area | Surgical prophylaxis / Infection prevention |
| Phase | Phase 3 |
Mechanism of action
Preoperative prophylactic antibiotics work by achieving adequate tissue and serum concentrations at the time of surgical incision to suppress or eliminate bacteria that could contaminate the surgical wound. The choice and timing of antibiotics depend on the type of surgery and local microbial flora, with the goal of reducing postoperative infection rates without promoting unnecessary antibiotic resistance.
Approved indications
- Surgical site infection prevention in elective surgical procedures
Common side effects
- Allergic reaction (rash, urticaria)
- Gastrointestinal disturbance
- Anaphylaxis (rare)
Key clinical trials
- Acupuncture for Colorectal sUrgery Recovery Enhancement: A Randomized Controlled Trial Evaluating Gastrointestinal Functional Recovery After Minimally Invasive Resection (NA)
- IO Vancomycin Spine (PHASE2, PHASE3)
- Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity (PHASE2, PHASE3)
- De-implementing PreOp Urine Testing (NA)
- Azithromycin Prophylaxis for PRElabor CEsarean DElivery Trial (PHASE3)
- The Contribution of Accelerated Recovery (mERAS) Approach to Postoperative Recovery in Pediatric Laparoscopic Surgery Cases (NA)
- NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS) (PHASE1, PHASE2)
- IO Vancomycin Into the Medial Malleolus vs IV Administration in Revision TKA (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Standard of Care Preoperative antibiotics CI brief — competitive landscape report
- Standard of Care Preoperative antibiotics updates RSS · CI watch RSS
- The George Washington University Biostatistics Center portfolio CI
Frequently asked questions about Standard of Care Preoperative antibiotics
What is Standard of Care Preoperative antibiotics?
How does Standard of Care Preoperative antibiotics work?
What is Standard of Care Preoperative antibiotics used for?
Who makes Standard of Care Preoperative antibiotics?
What drug class is Standard of Care Preoperative antibiotics in?
What development phase is Standard of Care Preoperative antibiotics in?
What are the side effects of Standard of Care Preoperative antibiotics?
Related
- Drug class: All Prophylactic antibiotic regimen drugs
- Manufacturer: The George Washington University Biostatistics Center — full pipeline
- Therapeutic area: All drugs in Surgical prophylaxis / Infection prevention
- Indication: Drugs for Surgical site infection prevention in elective surgical procedures
- Compare: Standard of Care Preoperative antibiotics vs similar drugs
- Pricing: Standard of Care Preoperative antibiotics cost, discount & access