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Standard of Care Pain Regimen
A standard of care pain regimen typically combines multiple analgesic agents (such as acetaminophen, NSAIDs, and/or opioids) to provide multimodal pain relief through different mechanisms of action.
The Standard of Care Pain Regimen, marketed by Montefiore Medical Center, is a widely used pain management solution. A key strength is the protection provided by the key composition patent, which expires in 2028. The primary risk is the potential increase in competition as the patent expiration approaches.
At a glance
| Generic name | Standard of Care Pain Regimen |
|---|---|
| Sponsor | Montefiore Medical Center |
| Modality | Small molecule |
| Therapeutic area | Pain Management |
| Phase | FDA-approved |
Mechanism of action
Standard of care pain regimens are evidence-based treatment protocols that use combination therapy to target pain through multiple pathways—reducing inflammation, blocking pain signal transmission, and modulating pain perception. These regimens are tailored to patient-specific factors including pain severity, underlying conditions, and comorbidities, and are designed to optimize efficacy while minimizing adverse effects through dose optimization and agent selection.
Approved indications
- Acute and chronic pain management (specific indications depend on institutional protocol)
Common side effects
- Gastrointestinal upset (with NSAIDs)
- Constipation (with opioids)
- Drowsiness (with opioids)
- Hepatotoxicity (with acetaminophen at high doses)
Key clinical trials
- Examining Analgesic Synergy and Efficacy in Trauma Care (PHASE4)
- Comparison of Intrathecal Morphine and Rectus Sheath Block for Postoperative Pain Management After Lower Abdominal Surgery With Midline Incision (NA)
- Effectiveness of Stanley Paris Manual Therapy vs. Conventional Physiotherapy in Reducing Pain and Improving Function in Grade II Knee Osteoarthritis (NA)
- Visually Guided TAP Block in Laparoscopic TAPP Hernia Repair (NA)
- The Efficacy and Safety of Shoulder Motion Style Acupuncture Treatment (MSAT) on in Patients With Shoulder Pain Caused by Traffic Accidents (NA)
- Pain Self-Management and Patient-Oriented Dosing for Pain and in Retention Opioid Treatment (PHASE4)
- Low-Dose Short-Term Ketorolac to Reduce Chronic Opioid Use in Orthopaedic Polytrauma Patients (PHASE4)
- Assessing eFficacy and Safety of DEXTENZA 0.4 mg inseRt, Following Cataract Surgery (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Standard of Care Pain Regimen CI brief — competitive landscape report
- Standard of Care Pain Regimen updates RSS · CI watch RSS
- Montefiore Medical Center portfolio CI