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Standard of Care - Double Oral
Standard of Care - Double Oral is a Antithrombotic combination therapy Small molecule drug developed by AOP Orphan Pharmaceuticals AG. It is currently FDA-approved for Acute coronary syndrome, Post-percutaneous coronary intervention, Atrial fibrillation with additional thrombotic risk.
This is a standard-of-care dual oral antithrombotic regimen combining two antiplatelet or anticoagulant agents to prevent thrombotic events.
This is a standard-of-care dual oral antithrombotic regimen combining two antiplatelet or anticoagulant agents to prevent thrombotic events. Used for Acute coronary syndrome, Post-percutaneous coronary intervention, Atrial fibrillation with additional thrombotic risk.
At a glance
| Generic name | Standard of Care - Double Oral |
|---|---|
| Sponsor | AOP Orphan Pharmaceuticals AG |
| Drug class | Antithrombotic combination therapy |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular |
| Phase | FDA-approved |
Mechanism of action
Double oral therapy typically refers to a combination of oral antiplatelet agents (such as aspirin and clopidogrel) or an oral anticoagulant with an antiplatelet agent, used to reduce the risk of thrombotic complications in cardiovascular conditions. The exact mechanism depends on the specific drug combination, but generally involves inhibition of platelet aggregation and/or coagulation cascade to prevent clot formation.
Approved indications
- Acute coronary syndrome
- Post-percutaneous coronary intervention
- Atrial fibrillation with additional thrombotic risk
Common side effects
- Bleeding
- Gastrointestinal hemorrhage
- Dyspepsia
Key clinical trials
- A Study of Milvexian in Participants After a Recent Acute Coronary Syndrome (PHASE3)
- Syk Inhibition in MItigating Lung Allograft Rejection (SIMILAR): A Trial to Evaluate the Safety and Tolerability of Fostamatinib in Lung Transplant Patients With Donor-Specific Antibodies (PHASE1)
- Evaluation of CRS3123 vs. Oral Vancomycin in Adult Patients With Clostridioides Difficile Infection (PHASE2)
- Efficacy of Gou-Teng-San (GTS) in Patients With Episodic Migraine: A Double-Blind Randomized Controlled Trial (PHASE3)
- A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular Atrophy (PHASE2)
- Effects of Red and Infrared Photobiomodulation in Rhinoplasty at a Single Centre (NA)
- Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer (PHASE3)
- SHAPE-ENDO: Multimodal Pre-Surgical Optimization in Patients With Obesity and Early-Stage Endometrial Cancer
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Standard of Care - Double Oral CI brief — competitive landscape report
- Standard of Care - Double Oral updates RSS · CI watch RSS
- AOP Orphan Pharmaceuticals AG portfolio CI
Frequently asked questions about Standard of Care - Double Oral
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Related
- Drug class: All Antithrombotic combination therapy drugs
- Manufacturer: AOP Orphan Pharmaceuticals AG — full pipeline
- Therapeutic area: All drugs in Cardiovascular
- Indication: Drugs for Acute coronary syndrome
- Indication: Drugs for Post-percutaneous coronary intervention
- Indication: Drugs for Atrial fibrillation with additional thrombotic risk
- Compare: Standard of Care - Double Oral vs similar drugs
- Pricing: Standard of Care - Double Oral cost, discount & access