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Standard multimodal pain management regimen
A multimodal pain management regimen combines multiple analgesic agents and techniques with different mechanisms of action to provide synergistic pain relief.
A multimodal pain management regimen combines multiple analgesic agents and techniques with different mechanisms of action to provide synergistic pain relief. Used for Acute postoperative pain, Chronic pain conditions, Cancer pain.
At a glance
| Generic name | Standard multimodal pain management regimen |
|---|---|
| Sponsor | Thomas L Bradbury |
| Modality | Small molecule |
| Therapeutic area | Pain Management |
| Phase | FDA-approved |
Mechanism of action
Standard multimodal pain management typically integrates opioids, non-opioid analgesics (such as NSAIDs or acetaminophen), adjuvant medications (such as gabapentinoids or antidepressants), and non-pharmacological interventions to target pain through multiple pathways simultaneously. This approach aims to optimize analgesia while reducing the required dose of any single agent, thereby minimizing adverse effects and improving overall pain control.
Approved indications
- Acute postoperative pain
- Chronic pain conditions
- Cancer pain
- Perioperative pain management
Common side effects
- Nausea and vomiting
- Constipation
- Dizziness
- Sedation
- Drug interactions
Key clinical trials
- Examining Analgesic Synergy and Efficacy in Trauma Care (PHASE4)
- Acupuncture for Colorectal sUrgery Recovery Enhancement: A Randomized Controlled Trial Evaluating Gastrointestinal Functional Recovery After Minimally Invasive Resection (NA)
- Continous Infusion of Nefopam for Patients Undergoing Pancreatoduodenectomy (PHASE4)
- Opioid Free and Opioid Based Anesthesia in Elective Lumbar Spine Surgery
- Visually Guided TAP Block in Laparoscopic TAPP Hernia Repair (NA)
- A Study on Reducing Opioid Use After Minimally Invasive Ankle Surgery (NA)
- Low-Dose Short-Term Ketorolac to Reduce Chronic Opioid Use in Orthopaedic Polytrauma Patients (PHASE4)
- Percutaneous Cryoablation of Intercostal Nerves for the Treatment of Rib Fractures (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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