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SRP + Aloe
SRP + Aloe is a Herbal adjunct to mechanical periodontal therapy Small molecule drug developed by Dr. D. Y. Patil Dental College & Hospital. It is currently FDA-approved for Chronic periodontitis, Gingivitis. Also known as: Korphad Ghar.
SRP (Scaling and Root Planing) combined with Aloe vera promotes periodontal healing and reduces inflammation in gum disease through mechanical plaque removal and the antimicrobial and anti-inflammatory properties of Aloe.
Aloe Vera is a small molecule used in a clinical trial for the treatment of Chronic Periodontitis, specifically in the form of a gel. The trial, NCT03204097, also investigated the use of Alendronate, a small molecule, in combination with Aloe Vera for the treatment of furcation defects in Chronic Periodontitis.
At a glance
| Generic name | SRP + Aloe |
|---|---|
| Also known as | Korphad Ghar |
| Sponsor | Dr. D. Y. Patil Dental College & Hospital |
| Drug class | Herbal adjunct to mechanical periodontal therapy |
| Modality | Small molecule |
| Therapeutic area | Dentistry / Periodontics |
| Phase | FDA-approved |
Mechanism of action
SRP is a mechanical debridement procedure that removes calculus and biofilm from tooth surfaces and root surfaces below the gum line. Aloe vera is added as an adjunctive topical agent to enhance healing, reduce bacterial load, and modulate the inflammatory response in periodontal tissues. The combination aims to improve clinical outcomes in periodontal disease management.
Approved indications
- Chronic periodontitis
- Gingivitis
Common side effects
- Gum irritation
- Allergic reaction to Aloe
- Tooth sensitivity
Key clinical trials
- Flurbiprofen Versus Aloe Vera Gel in the Treatment of Chronic Periodontitis in Smoking Patients. (PHASE4)
- Evaluation of Local Delivery of Aloe Vera Gel as an Adjunct to Non-surgical Treatment in Patients With Chronic Periodontitis (NA)
- Local Host Modulating Agents Alendronate & Aloe Vera for Treatment of Furcation Defects in Chronic Periodontitis (PHASE2, PHASE3)
- Efficacy of AloeVera Gel Gum Massaging and Adjunct to Scaling and Root Planing in Chronic Periodontitis Patients (NA)
- Local Drug Delivery of Aloe Vera Gel in Chronic Periodontitis (PHASE2, PHASE3)
- Locally Delivered Aloe Vera Gel in the Treatment of Chronic Periodontitis Patients With Diabetes Mellitus (PHASE4)
- Aloe Vera in Chronic Periodontitis With Type 2 Diabetes Mellitus (PHASE2, PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- SRP + Aloe CI brief — competitive landscape report
- SRP + Aloe updates RSS · CI watch RSS
- Dr. D. Y. Patil Dental College & Hospital portfolio CI
Frequently asked questions about SRP + Aloe
What is SRP + Aloe?
How does SRP + Aloe work?
What is SRP + Aloe used for?
Who makes SRP + Aloe?
Is SRP + Aloe also known as anything else?
What drug class is SRP + Aloe in?
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Related
- Drug class: All Herbal adjunct to mechanical periodontal therapy drugs
- Manufacturer: Dr. D. Y. Patil Dental College & Hospital — full pipeline
- Therapeutic area: All drugs in Dentistry / Periodontics
- Indication: Drugs for Chronic periodontitis
- Indication: Drugs for Gingivitis
- Also known as: Korphad Ghar
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing