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SOLRIAMFETOL HYDROCHLORIDE
SOLRIAMFETOL HYDROCHLORIDE is a drug. It is currently FDA-approved (first approved 2019).
Solemidetol hydrochloride, also known as JZP-110, is being studied for its potential to treat excessive sleepiness, Parkinson's disease, narcolepsy, and obstructive sleep apnea. It is a compound that has undergone clinical trials to assess its safety, efficacy, and pharmacokinetics in these conditions.
At a glance
| Generic name | SOLRIAMFETOL HYDROCHLORIDE |
|---|---|
| Modality | Small molecule |
| Phase | FDA-approved |
| First approval | 2019 |
Approved indications
Common side effects
- Headache
- Nausea
- Decreased appetite
- Insomnia
- Anxiety
- Bruxism
- Diarrhea
- Dry mouth
- Weight decreased
- Cough
- Agitation
- Irritability
Serious adverse events
- Palpitations
- Dyspnea
- Constipation
- Vomiting
Key clinical trials
- A 4-Week Study of the Safety, Efficacy, and Pharmacokinetics of JZP-110 [(R)-2-amino-3-phenylpropylcarbamate Hydrochloride] in Subjects With Parkinson's Disease and Excessive Sleepiness (PHASE2)
- "Six-week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in OSA" (PHASE3)
- "Twelve-week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in Narcolepsy" (PHASE3)
- "Twelve-week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in OSA" (PHASE3)
- "A Long-Term Safety Study of JZP-110 in the Treatment of Excessive Sleepiness in Subjects With Narcolepsy or OSA" (PHASE3)
Patents
| Patent | Expiry | Type |
|---|---|---|
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| FDA label | Mechanism, indications, dosing, boxed warnings, drug interactions |
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
| FDA Orange Book | Patents + exclusivity |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- SOLRIAMFETOL HYDROCHLORIDE CI brief — competitive landscape report
- SOLRIAMFETOL HYDROCHLORIDE updates RSS · CI watch RSS
Frequently asked questions about SOLRIAMFETOL HYDROCHLORIDE
What is SOLRIAMFETOL HYDROCHLORIDE?
When was SOLRIAMFETOL HYDROCHLORIDE approved?
What development phase is SOLRIAMFETOL HYDROCHLORIDE in?
What are the side effects of SOLRIAMFETOL HYDROCHLORIDE?
Related
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing