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Solaraze 3% Topical Gel
Solaraze 3% Topical Gel is a topical gel formulation of tazarotene, a retinoid that modulates the expression of genes involved in cell proliferation and differentiation.
Solaraze 3% Topical Gel is a topical gel formulation of tazarotene, a retinoid that modulates the expression of genes involved in cell proliferation and differentiation. Used for Moderate to severe plaque psoriasis.
At a glance
| Generic name | Solaraze 3% Topical Gel |
|---|---|
| Sponsor | Encube Ethicals Pvt. Ltd. |
| Drug class | retinoid |
| Target | retinoic acid receptors |
| Modality | Small molecule |
| Therapeutic area | Dermatology |
| Phase | Phase 3 |
Mechanism of action
Tazarotene works by binding to retinoic acid receptors, which are transcription factors that regulate the expression of genes involved in cell growth and differentiation. This leads to an inhibition of cell proliferation and an induction of cell differentiation, resulting in a reduction in the severity of psoriasis symptoms.
Approved indications
- Moderate to severe plaque psoriasis
Common side effects
- burning sensation
- redness
- itching
Key clinical trials
- Counterpain PXM Versus Diclofenac Versus Piroxicam (PHASE3)
- Home-Based Strategies for Knee Osteoarthritis (NA)
- Effects of Photobiomodulation and Topical Diclofenac on Inflammation and Pain in Knee Osteoarthritis (EPIC-KO) (PHASE2)
- To Check Dermatological Safety of Test Products by 24 Hours Patch Testing (NA)
- Exercise vs. Topical Diclofenac vs. PRP (NA)
- Topical Diclofenac vs.Oral Ibuprofen for MSK Pain in Children (PHASE3)
- Assessment of Ozone Therapy for Management of Post-Extraction Localized Alveolar Osteitis (NA)
- Topical Diclofenac for Prevention of Radiation-induced Dermatitis (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Solaraze 3% Topical Gel CI brief — competitive landscape report
- Solaraze 3% Topical Gel updates RSS · CI watch RSS
- Encube Ethicals Pvt. Ltd. portfolio CI