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SodiumChloride
Sodium chloride replaces electrolytes and restores osmotic balance in body fluids.
Sodium chloride replaces electrolytes and restores osmotic balance in body fluids. Used for Electrolyte replacement in hyponatremia or sodium depletion, Fluid and electrolyte maintenance in intravenous therapy, Dehydration management.
At a glance
| Generic name | SodiumChloride |
|---|---|
| Also known as | Placebo |
| Sponsor | Radboud University Medical Center |
| Drug class | Electrolyte replacement |
| Modality | Small molecule |
| Therapeutic area | General/Supportive Care |
| Phase | Phase 3 |
Mechanism of action
Sodium chloride is an essential electrolyte that maintains proper fluid balance, nerve conduction, and muscle contraction. It is used to restore sodium and chloride levels in patients with deficiency or dehydration, and to maintain physiological osmolarity in intravenous solutions.
Approved indications
- Electrolyte replacement in hyponatremia or sodium depletion
- Fluid and electrolyte maintenance in intravenous therapy
- Dehydration management
Common side effects
- Hypernatremia (elevated sodium)
- Fluid overload
- Phlebitis (at IV site)
- Hypertension
Key clinical trials
- An Explorative Psoriasis Biomarker Study (NA)
- Effect of Ferric Carboxymaltose on Exercise Capacity After Kidney Transplantation (PHASE3)
- Erector Spinae Plane Block as Pain Management After Lumbar Fusion Surgery (PHASE4)
- New Truncal Nerve Blocks for Thoracoscopic Surgery and Open Heart Surgery. (PHASE4)
- The Effect of Clonidine-enhanced Sedation on Delirium in Ventilated Critically Ill Patients (PHASE3)
- Acute Unilateral Vestibulopathy and Corticosteroid Treatment (PHASE4)
- Wishing to Decrease Aquaresis in ADPKD Patients Treated With a V2Ra; the Effect of Regulating Protein and Salt (NA)
- Fluid Kinetics in Patients With Diabetic Ketoacidosis (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- SodiumChloride CI brief — competitive landscape report
- SodiumChloride updates RSS · CI watch RSS
- Radboud University Medical Center portfolio CI