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Sodium Lactate In Plastic Container (SODIUM LACTATE)
Potassium Chloride in Lactated Ringer’s and Dextrose (5%) Injection provides water, electrolytes, and calories, and helps regulate fluid balance, acid-base equilibrium, and energy metabolism.
Sodium Lactate is a small molecule drug originally developed by Baxter Healthcare and currently owned by Hospira. It was FDA approved in 1971 for the treatment of hypokalemia and prevention of hypokalemia. The commercial status of Sodium Lactate is off-patent, meaning there are no active Orange Book patents. Key safety considerations include the potential for electrolyte imbalances. It is used to treat low potassium levels in the blood.
At a glance
| Generic name | SODIUM LACTATE |
|---|---|
| Sponsor | Pfizer |
| Drug class | sodium lactate |
| Modality | Small molecule |
| Therapeutic area | Hematology |
| Phase | FDA-approved |
| First approval | 1971 |
Mechanism of action
This solution contains potassium, sodium, chloride, calcium, and dextrose, which work together to maintain fluid balance, electrolyte levels, and acid-base equilibrium. It also provides calories and supports carbohydrate and protein metabolism, helping to prevent metabolic acidosis and ketosis.
Approved indications
- Electrolyte and Caloric Support
- Alkalinizing Agent
Common side effects
- Hypervolemia
- Hypovolemia
- Fluid retention
- Hypokalemia
- Hyponatremia
- Dehydration
- Hypochloremia
- Hypotension
- Hypertension
- Dyspnea
- Sclerosing encapsulating peritonitis
- Peritoneal cloudy effluent
Drug interactions
- Drugs that Affect Electrolyte and/or Fluid Balance
- Lithium
- Digoxin
- Drugs with pH-Dependent Renal Elimination
Key clinical trials
- Evaluation of Intravenous Sodium Valproate on Interleukin-6 Levels in Patients With TMJ Disc Displacement (PHASE2)
- Venous Congestion And Cognitive Dysfunction After Cardiac Surgery
- Efficacy of Autologous Conditioned Serum in Temporomandibular Joint Disorder (NA)
- Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis (PHASE3)
- The AminoECMO Pilot Trial (PHASE2)
- Crystalloid vs Colloid for Hemodynamics During Anesthesia Induction in TAVR Patients (NA)
- Role of Elevated Lactate Levels on Lipid and Carbohydrate Metabolism. (NA)
- Antibacterial Mouthwash for Pharyngeal Gonorrhea Prevention (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| FDA label | Mechanism, indications, dosing, boxed warnings, drug interactions |
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Sodium Lactate In Plastic Container CI brief — competitive landscape report
- Sodium Lactate In Plastic Container updates RSS · CI watch RSS
- Pfizer portfolio CI