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Sodium Hypochlorite Solution
Sodium hypochlorite solution acts as a broad-spectrum antimicrobial agent by releasing hypochlorous acid, which oxidizes and destroys bacterial, viral, and fungal cell components.
Sodium hypochlorite solution acts as a broad-spectrum antimicrobial agent by releasing hypochlorous acid, which oxidizes and destroys bacterial, viral, and fungal cell components. Used for Wound irrigation and disinfection, Surface disinfection and sterilization, Oral rinse for oral hygiene.
At a glance
| Generic name | Sodium Hypochlorite Solution |
|---|---|
| Also known as | NaOCl, NaOCl group |
| Sponsor | University of Sulaimani |
| Drug class | Disinfectant/Antiseptic |
| Modality | Small molecule |
| Therapeutic area | Infection Control / Disinfection |
| Phase | FDA-approved |
Mechanism of action
Sodium hypochlorite dissociates in aqueous solution to form hypochlorous acid (HOCl), a potent oxidizing agent. This oxidative action disrupts microbial cell membranes, denatures proteins, and damages nucleic acids, leading to rapid microbial death. It is non-selective and effective against a wide range of pathogens including bacteria, viruses, fungi, and spores.
Approved indications
- Wound irrigation and disinfection
- Surface disinfection and sterilization
- Oral rinse for oral hygiene
- Water purification
Common side effects
- Skin irritation or chemical burn (with concentrated solutions)
- Eye irritation or damage (with direct contact)
- Respiratory irritation (from vapors)
- Allergic contact dermatitis
Key clinical trials
- Comparison of Two Minimally Invasive Approaches for Masking Molar-Incisor Hypomineralization Opacities (NA)
- EUSOL vs. PDGF Dressing for Diabetic Foot Ulcers (NA)
- Epigallocatechin Gallate (EGCG) as a Flushing Agent During Full Pulpotomy in Mature Permanent Molars With Irreversible Pulpitis (NA)
- Comparison of Post-Operative Endodontic Pain Using Sodium Hypochlorite, Hydrogen Peroxide, and Normal Saline as Root Canal Irrigants (NA)
- Lesion Sterilization and Tissue Repair Antibiotic Paste Versus Zinc Oxide and Eugenol Pulpectomy for Treatment of Primary Molars With Pulp Necrosis (PHASE1, PHASE2)
- Non-Surgical Treatment of Periodontitis With Adjunctive Sodium Hypochlorite/Amino Acids and Cross-Linked Hyaluronic Acid (NA)
- Evaluating Postoperative Pain and Antibacterial Effect of Ultrasonic and 980 nm Diode Laser Combination (NA)
- Effects of Treatments on Atopic Dermatitis (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Sodium Hypochlorite Solution CI brief — competitive landscape report
- Sodium Hypochlorite Solution updates RSS · CI watch RSS
- University of Sulaimani portfolio CI