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Sodium Chloride 0.9 % Nasal Spray
Sodium chloride 0.9% nasal spray provides isotonic saline irrigation to cleanse and moisturize nasal passages.
Sodium chloride 0.9% nasal spray provides isotonic saline irrigation to cleanse and moisturize nasal passages. Used for Nasal congestion relief, Nasal irrigation and cleansing, Allergic rhinitis symptom management.
At a glance
| Generic name | Sodium Chloride 0.9 % Nasal Spray |
|---|---|
| Also known as | Intranasal Saline Spray |
| Sponsor | Murdoch Childrens Research Institute |
| Drug class | Saline nasal irrigation solution |
| Modality | Small molecule |
| Therapeutic area | Otolaryngology / Nasal care |
| Phase | FDA-approved |
Mechanism of action
This is a physiologic saline solution (0.9% NaCl) that matches the osmolarity of human blood and tissues. When sprayed into the nasal cavity, it helps clear mucus, allergens, and irritants while providing hydration to nasal mucosa. It is a non-medicated, mechanical intervention with no pharmacologic targets.
Approved indications
- Nasal congestion relief
- Nasal irrigation and cleansing
- Allergic rhinitis symptom management
- Post-nasal drip management
Common side effects
- Nasal irritation
- Mild stinging or burning
- Epistaxis (rare)
Key clinical trials
- Neural Mechanisms of Immersive Virtual Reality in Chronic Pain (PHASE1, PHASE2)
- Assessing Role of Probiotics in Children Aged 6-36 Months Treated for Pneumonia (NA)
- Safety and Efficacy of Human Adipose-Derived Stem Cell Exosomes in Acute Ischemic Stroke (PHASE1, PHASE2)
- Nasal Decongestant to Reduce Perioperative Adverse Events in Children With Upper Respiratory Track Infections Having Anesthesia. (PHASE4)
- Effects of Intranasal Oxytocin on Sexual Well-Being in Patients With Arginine Vasopressin Deficiency and Healthy Controls (PHASE2)
- Intranasal Steroid as Medical Therapy For Sleep-Disordered Breathing in Children (PHASE4)
- Nitric Oxide Nasal Spray (NONS) as Prevention for Treatment of Individuals at Risk of Exposure to COVID-19 Infection (PHASE3)
- Intra Nasal Sufentanil Versus Intravenous Morphine for Acute Severe Traumatic Pain Analgesia in Emergency Setting (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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