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Sodium Chloride [0.9%]
Sodium chloride 0.9% is an isotonic saline solution that replaces fluid and electrolytes lost through dehydration, bleeding, or other causes.
Sodium chloride 0.9% is an isotonic saline solution that replaces fluid and electrolytes lost through dehydration, bleeding, or other causes. Used for Hypovolemia and dehydration, Perioperative fluid replacement, Maintenance of vascular access.
At a glance
| Generic name | Sodium Chloride [0.9%] |
|---|---|
| Also known as | Physiologic Saline Solution, Normal Saline |
| Sponsor | Fundacion Clinica Valle del Lili |
| Drug class | Crystalloid fluid / Electrolyte replacement |
| Modality | Small molecule |
| Therapeutic area | Fluid and Electrolyte Management |
| Phase | FDA-approved |
Mechanism of action
This solution contains sodium and chloride ions in physiologic concentrations (0.9% w/v) that match blood plasma osmolality, allowing safe intravenous or topical administration without causing cell lysis or crenation. It restores intravascular volume and maintains electrolyte balance, supporting cardiovascular stability and tissue perfusion.
Approved indications
- Hypovolemia and dehydration
- Perioperative fluid replacement
- Maintenance of vascular access
- Wound irrigation and topical use
Common side effects
- Hyperchloremic acidosis
- Fluid overload / pulmonary edema
- Hypernatremia
- Phlebitis at infusion site