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SOC 4F-PCC

Takeda · Phase 3 active Small molecule

SOC 4F-PCC is a Factor IIa protease-activated receptor 1 (PAR-1) antagonist that inhibits thrombin signaling to reduce thrombotic events.

SOC 4F-PCC is a Factor IIa protease-activated receptor 1 (PAR-1) antagonist that inhibits thrombin signaling to reduce thrombotic events. Used for Acute coronary syndrome (Phase 3).

At a glance

Generic nameSOC 4F-PCC
SponsorTakeda
Drug classPAR-1 antagonist
TargetPAR-1 (Protease-Activated Receptor 1)
ModalitySmall molecule
Therapeutic areaCardiovascular
PhasePhase 3

Mechanism of action

The drug blocks PAR-1, a G-protein coupled receptor activated by thrombin, which plays a key role in platelet activation and thrombosis. By antagonizing PAR-1, SOC 4F-PCC reduces pathological clot formation while potentially preserving hemostasis. This mechanism is distinct from conventional anticoagulants and antiplatelet agents.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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