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Skin antisepsis
Skin antisepsis reduces or eliminates microorganisms on the skin surface to prevent infection during medical procedures.
Skin antisepsis reduces or eliminates microorganisms on the skin surface to prevent infection during medical procedures. Used for Preoperative skin antisepsis prior to surgical procedures, Skin disinfection prior to invasive medical procedures.
At a glance
| Generic name | Skin antisepsis |
|---|---|
| Sponsor | University of British Columbia |
| Drug class | Topical antiseptic |
| Modality | Small molecule |
| Therapeutic area | Infection Prevention |
| Phase | FDA-approved |
Mechanism of action
Antiseptic agents work by disrupting bacterial cell membranes, denaturing proteins, or interfering with microbial metabolism, thereby killing or inhibiting the growth of pathogenic organisms on the skin. This reduces the microbial load at the site of surgical or invasive procedures, lowering the risk of surgical site infections and other procedure-related infections.
Approved indications
- Preoperative skin antisepsis prior to surgical procedures
- Skin disinfection prior to invasive medical procedures
Common side effects
- Skin irritation or erythema
- Allergic contact dermatitis
- Drying of skin
Key clinical trials
- CLinical Evaluation of ANtiseptic Skin Preparation in Revision Total Joint Arthroplasty of the Hip and Knee (NA)
- Erector Spinae Plane Block Versus Transcutaneous Radiofrequency in Postherpetic Neuralgia
- Post Facilitatiion Stretch and Dry Needling on Hamstring Tightness in Chronic Low Back Pain (NA)
- Effect of Bed Bathing Methods on VRE Colonization in ICU Patients (NA)
- Comparison of the Analgesic Efficacy of Erector Spinae Plane Block in Breast-Conserving Surgery Versus Serratus Anterior Block Combined With Additional Pecto-Intercostal II Block (NA)
- Pre-Incision Peripheral Nerve Blocks for Lower Extremity Fracture Surgery in Older Adults (PHASE4)
- Staph Intervention for Effective Local Defense (PHASE4)
- Comparison of Sympathetic Blockade Duration in Brachial Plexus Blocks Performed by Different Methods (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |