Last reviewed · How we verify

Sitafloxacin (S)

Shenzhen Third People's Hospital · Phase 3 active Small molecule

Sitafloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV.

Sitafloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV. Used for Community-acquired pneumonia, Nosocomial pneumonia, Skin and soft tissue infections.

At a glance

Generic nameSitafloxacin (S)
SponsorShenzhen Third People's Hospital
Drug classfluoroquinolone antibiotic
TargetDNA gyrase and topoisomerase IV
ModalitySmall molecule
Therapeutic areaInfectious diseases
PhasePhase 3

Mechanism of action

This inhibition prevents bacterial DNA replication and transcription, ultimately leading to bacterial cell death. Sitafloxacin's mechanism of action is similar to other fluoroquinolones, but with a broader spectrum of activity against Gram-positive and Gram-negative bacteria.

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape: