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single injection nerve block
A single injection nerve block temporarily interrupts nerve signal transmission to provide localized anesthesia and pain relief.
A single injection nerve block temporarily interrupts nerve signal transmission to provide localized anesthesia and pain relief. Used for Perioperative pain management and anesthesia, Chronic pain conditions requiring regional anesthesia.
At a glance
| Generic name | single injection nerve block |
|---|---|
| Sponsor | University of California, San Diego |
| Drug class | Local anesthetic nerve block |
| Modality | Small molecule |
| Therapeutic area | Pain Management / Anesthesia |
| Phase | FDA-approved |
Mechanism of action
Nerve blocks work by delivering local anesthetic agents directly around peripheral nerves, blocking the conduction of pain signals from a specific anatomical region. This approach provides targeted anesthesia without systemic effects, allowing for pain control during and after procedures or for chronic pain management. The effect is temporary, lasting from hours to days depending on the anesthetic agent and formulation used.
Approved indications
- Perioperative pain management and anesthesia
- Chronic pain conditions requiring regional anesthesia
Common side effects
- Temporary nerve injury or paresthesia
- Hematoma or bruising at injection site
- Local anesthetic toxicity (if systemic absorption occurs)
- Infection at injection site
Key clinical trials
- Effect of Scalp Block on Intraoperative Hemodynamics and Postoperative Pain in Craniotomy Patients" (NA)
- Serratus Plane Block (SPB) Versus Capsaïcine Versus Botox-A for Chronic Neuropathic Pain in Post-mastectomy Syndrome (PHASE2)
- Jaw Muscle Pain Post Wisdom Molar Surgery (PHASE2)
- Intercostal Nerve Cryoablation Versus Epidural Analgesia for Nuss Repair of Pectus Excavatum (NA)
- A Comparison Between a PC and a CC Approach for the Placement of Infraclavicular Perineural Catheters in Hand Surgery (NA)
- COMPARISON OF OBTURATOR NERVE BLOCK TECHNIQUES IN TURBT (NA)
- Intertransverse Process Block to Improve Quality of Recovery and Pain Management in Adult Cardiac Surgical Patients (NA)
- From Battlefield to Recovery: Continuous Regional Anaesthesia for War-Related Lower Limb Trauma
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- single injection nerve block CI brief — competitive landscape report
- single injection nerve block updates RSS · CI watch RSS
- University of California, San Diego portfolio CI