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Sindillimab

Xin-Hua Xu · Phase 2 active Small molecule ✓ Verified May 2026

Sindillimab is a Small molecule drug developed by Xin-Hua Xu. It is currently in Phase 2 development. Also known as: Pembrolizumab, Nivolumab, Durvalumab.

Sindillimab is being studied in clinical trials for the treatment of Non-small Cell Lung Cancer, Third-line Treatment, Advanced Duodenal Adenocarcinoma, and in combination with furquimatinib and sintilimab. The exact mechanism of action of Sindillimab is not specified in the provided information, but it is being studied in combination with other treatments, including sintilimab, which is a PD-1 inhibitor.

Likelihood of approval
15.3% vs 15.3% industry baseline
If approved by FDA: likely 2031–2034
Steps remaining: Phase 3 → NDA/BLA submission
Confidence: Medium
Why this estimate
  • Baseline phase 2 → approval rate +15.3pp
    Industry-wide phase 2 drugs reach approval ~15.3% of the time (BIO/Informa 2023 industry benchmark across all therapeutic areas).
Predicted approval windows by jurisdiction (conditional on FDA approval)
Regulator Country Likely year Lag vs FDA
FDA US 2031–2034
EMA EU 2032–2035 +0.7 yr
MHRA GB 2032–2035 +0.7 yr
Health Canada CA 2032–2036 +0.9 yr
TGA AU 2032–2036 +1.2 yr
PMDA JP 2032–2036 +1.5 yr
NMPA CN 2033–2037 +2.3 yr
MFDS KR 2032–2036 +1.4 yr
CDSCO IN 2032–2037 +1.8 yr
ANVISA BR 2033–2037 +2.3 yr

Hover any row for the lag rationale. Lag estimates are reduced when the drug has FDA Breakthrough or EMA PRIME designation (sponsors file globally in parallel).

Estimate based on the BIO/Informa industry phase transition rates plus per-drug modifiers for therapeutic area, sponsor type, FDA designations, mechanism, and trial design. Per-jurisdiction lags from Tufts CSDD international approval studies. Not investment, clinical or regulatory advice. Methodology: /methodology#likelihood.

At a glance

Generic nameSindillimab
Also known asPembrolizumab, Nivolumab, Durvalumab
SponsorXin-Hua Xu
ModalitySmall molecule
Therapeutic areaOther
PhasePhase 2

Approved indications

No approved indications tracked.

Common side effects

No common side effects on file.

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Frequently asked questions about Sindillimab

What is Sindillimab?

Sindillimab is a Small molecule drug developed by Xin-Hua Xu.

Who makes Sindillimab?

Sindillimab is developed by Xin-Hua Xu (see full Xin-Hua Xu pipeline at /company/xin-hua-xu).

Is Sindillimab also known as anything else?

Sindillimab is also known as Pembrolizumab, Nivolumab, Durvalumab.

What development phase is Sindillimab in?

Sindillimab is in Phase 2.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing