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SIMETHICONE
SIMETHICONE is a drug. It is currently FDA-approved (first approved 1996).
Simethicone is an antifoaming agent used to treat various gastrointestinal conditions, including Irritable Bowel Syndrome, as seen in clinical trials. It is used as an on-demand medication, such as in the study "Assessment of On-demand MeteoSpasmyl Use Effectiveness in Irritable Bowel Syndrome".
At a glance
| Generic name | SIMETHICONE |
|---|---|
| Phase | FDA-approved |
| First approval | 1996 |
Approved indications
Common side effects
Key clinical trials
- Robot-controlled Magnet-Assisted Capsule Endoscopy (NA)
- Effects of Pre-procedure and Intra-procedure Simethicone and Dicyclomine Administration in Improving Quality of Endoscopic Reterograde Cholangipancreaticography (ERCP) (PHASE4)
- 4-L Split-dose Polyethylene Glycol and Bisacodyl and Docusate Sodium Regimen Versus 2-L Split-dose Polyethylene Glycol Plus Oral Simethicone Regimen for Bowel Preparation Before Colonoscopy (NA)
- Effect of Simethicone on Helicobacter Pylori Detection in Routine Endoscopy (NA)
- Effect of Non-invasive Neuromodulation on the Quality of Intestinal Cleansing (NA)
- Hot Water Foot Bath for Pain and Gas Relief After Laparoscopic Cholecystectomy (NA)
- Double-blind, Randomized, Placebo-controlled Trial of Ganaxolone in CDKL5 Deficiency Patients 6 Months to Less Than 2 Years Old (PHASE3)
- Premedication With N-acetylcysteine and Simethicone to Improve Mucosal Visualization in Elective Upper Endoscopy (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| FDA label | Mechanism, indications, dosing, boxed warnings, drug interactions |
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- SIMETHICONE CI brief — competitive landscape report
- SIMETHICONE updates RSS · CI watch RSS
Frequently asked questions about SIMETHICONE
What is SIMETHICONE?
When was SIMETHICONE approved?
What development phase is SIMETHICONE in?
Related
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing