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Silver Colloid
Silver colloid exerts antimicrobial and anti-inflammatory effects through the release of silver ions that disrupt bacterial cell membranes and reduce inflammatory mediators.
Silver colloid exerts antimicrobial and anti-inflammatory effects through the release of silver ions that disrupt bacterial cell membranes and reduce inflammatory mediators. Used for Wound care and infection prevention, Topical antimicrobial applications.
At a glance
| Generic name | Silver Colloid |
|---|---|
| Also known as | Silver Hydrosyl by Sovereign Silver |
| Sponsor | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's |
| Drug class | Antimicrobial agent |
| Modality | Small molecule |
| Therapeutic area | Wound care / Infectious disease |
| Phase | FDA-approved |
Mechanism of action
Silver colloid consists of silver particles suspended in a liquid medium. The silver ions released from these particles have broad-spectrum antimicrobial activity against bacteria, fungi, and some viruses by interfering with cellular respiration and DNA replication. Additionally, silver colloid exhibits anti-inflammatory properties that may promote wound healing and tissue repair.
Approved indications
- Wound care and infection prevention
- Topical antimicrobial applications
Common side effects
- Argyria (skin discoloration from silver accumulation)
- Local irritation or sensitization
Key clinical trials
- Clinical Registry Collecting Real World Evidence on Wound Care Treatments
- Efficacy of a Polyhexanide Biguanide-Based Gel in the Prevention of Biofilm Formation in Pressure Ulcers (EARLY_PHASE1)
- Efficacy of Silver Diamine Fluoride Versus Nano-Silver Fluoride in Arresting Active Dentin Caries in Primary Teeth in Young Children (NA)
- Evaluation of Different Medicaments in the Management of Necrotic Primary Molars by Lesion Sterilization and Tissue Repair (NA)
- Children Acceptance of AgNP Mouthwash Against Chlorhexidine Mouthwash (NA)
- Comparative Study of Negative-Pressure Wound Therapy Integrated With Silver Nanoparticle Spray Versus Negative-Pressure Wound Therapy in Post-Revascularization Diabetic Foot Wound Management
- The Comparative Effects of Using 0.12% Chlorhexidine and Silver Nanoparticles Mouthwashes in Medical Students (PHASE3)
- Analyzing the Effect of Disinfection Additives on the Linear Dimensional Stability of Dental Alginate Impressions: A Quasi-Experimental Comparative Study (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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