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Sham laser plus topical clonazepam

Universidad Nacional Autonoma de Mexico · FDA-approved active Small molecule

Sham laser plus topical clonazepam combines a placebo laser procedure with a benzodiazepine applied to the skin to reduce anxiety and pain symptoms.

Sham laser plus topical clonazepam combines a placebo laser procedure with a benzodiazepine applied to the skin to reduce anxiety and pain symptoms. Used for Anxiety disorders (topical application), Neuropathic pain or localized pain conditions.

At a glance

Generic nameSham laser plus topical clonazepam
SponsorUniversidad Nacional Autonoma de Mexico
Drug classBenzodiazepine (topical) + sham procedure
TargetGABA-A receptor
ModalitySmall molecule
Therapeutic areaPsychiatry / Pain Management / Dermatology
PhaseFDA-approved

Mechanism of action

Clonazepam is a benzodiazepine that enhances GABAergic neurotransmission in the central nervous system, reducing anxiety and providing anxiolytic effects. When applied topically, it may provide localized anxiolytic and muscle-relaxant effects. The sham laser component serves as a control or placebo element in the treatment regimen.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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