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SER120
SER120 is a small molecule that targets the serotonin receptor.
SER120 is a small molecule that targets the serotonin receptor. Used for Treatment-resistant depression.
At a glance
| Generic name | SER120 |
|---|---|
| Sponsor | Serenity Pharmaceuticals, Inc. |
| Drug class | serotonin receptor antagonist |
| Target | 5-HT2A receptor |
| Modality | Small molecule |
| Therapeutic area | Psychiatry |
| Phase | Phase 3 |
Mechanism of action
It works by selectively binding to the serotonin receptor, which leads to a decrease in serotonin levels in the brain. This decrease in serotonin levels is thought to be beneficial for patients with certain conditions.
Approved indications
- Treatment-resistant depression
Common side effects
- Nausea
- Headache
- Dizziness
Key clinical trials
- Long Term Safety Assessment of SER120 in Patients With Nocturia (PHASE3)
- Study to Investigate the Safety and Pharmacokinetics of SER120 Nasal Spray in Elderly Patients With Nocturia (PHASE3)
- Multicenter Study to Investigate SER120 Nasal Spray Formulations in Patients With Nocturia - DB4 (PHASE3)
- Treatment of Patients With Nocturia (Non-PK Study) (PHASE3)
- Multicenter Study to Investigate SER120 Nasal Spray Formulations in Patients With Nocturia (PHASE2, PHASE3)
- Treatment of Patients With Nocturia (PHASE3)
Primary sources
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| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |