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semaglutide injection (HD1916)
Semaglutide injection works by mimicking the action of a natural hormone in the body called glucagon-like peptide-1 (GLP-1) to help lower blood sugar levels.
Semaglutide injection works by mimicking the action of a natural hormone in the body called glucagon-like peptide-1 (GLP-1) to help lower blood sugar levels. Used for Treatment of type 2 diabetes, Weight management in adults with obesity.
At a glance
| Generic name | semaglutide injection (HD1916) |
|---|---|
| Sponsor | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. |
| Drug class | GLP-1 receptor agonist |
| Target | GLP-1R |
| Modality | Small molecule |
| Therapeutic area | Diabetes |
| Phase | Phase 3 |
Mechanism of action
By activating GLP-1 receptors in the pancreas, semaglutide stimulates the release of insulin and decreases the production of glucagon, a hormone that raises blood sugar levels. This leads to improved glycemic control and weight loss.
Approved indications
- Treatment of type 2 diabetes
- Weight management in adults with obesity
Common side effects
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Injection site reactions
Key clinical trials
- Efficacy and Safety of Semaglutide Injection (HD1916) in Patients With Type 2 Diabetes Mellitus (PHASE3)
- Semaglutide in Treatment of Obesity (PHASE3)
Primary sources
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| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |