Last reviewed · How we verify
Selzentry
At a glance
| Generic name | Selzentry |
|---|---|
| Sponsor | Icahn School of Medicine at Mount Sinai |
| Target | Multidrug and toxin extrusion protein 1, C-C chemokine receptor type 5, C-C chemokine receptor type 5 |
| Modality | Small molecule |
| Therapeutic area | Infectious Disease |
| Phase | FDA-approved |
Approved indications
- CCR5 Tropic Drug Resistant HIV Infection
Common side effects
- Upper respiratory tract infection
- Pyrexia
- Herpes infection
- Appetite disorders
- Dizziness/postural dizziness
- Sinusitis
- Bronchitis
- Joint-related signs and symptoms
- Paresthesias and dysesthesias
- Constipation
- Sensory abnormalities
- Pain and discomfort
Serious adverse events
- Syncope
- Orthostatic hypotension
Key clinical trials
- Study of Cobicistat-Boosted Atazanavir (ATV/co), Cobicistat-Boosted Darunavir (DRV/co) and Emtricitabine/Tenofovir Alafenamide (F/TAF) in Children With HIV (PHASE2, PHASE3)
- Antiviral Clinical Trial for Long Covid-19 (PHASE2)
- Trial of Allogeneic Reduced-Intensity, HLA-Haploidentical Allogeneic Hematopoietic Cell Bone Marrow Transplantation Followed by Graft-versus-Host-Disease (GVHD) Prophylaxis With Cyclophosphamide, Bortezomib and Maraviroc for Hematologic Malignancies ... (PHASE1, PHASE2)
- This Study is Assessing the Safety and Efficacy of Immune Inhibition as a Treatment to Prevent Primary Graft Dysfunction (PHASE2)
- Trial to Evaluate the Interest of a Reductive Anti Retroviral Strategy Using Dual Therapy Inspite of Triple Therapy (PHASE3)
- Impact of Chemokine Receptor 5 (CCR5) Inhibition on Sarcoidosis Immunophenotypes (NA)
- Pharmacokinetic Study of Antiretroviral Drugs and Related Drugs During and After Pregnancy
- Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With a Complicated Regimen (PHASE2, PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |