Last reviewed · How we verify
sedative mixture
A sedative mixture that depresses the central nervous system to induce sedation and reduce anxiety.
A sedative mixture that depresses the central nervous system to induce sedation and reduce anxiety. Used for Sedation in clinical settings, Anxiety management.
At a glance
| Generic name | sedative mixture |
|---|---|
| Also known as | -Ultiva, -Diprivan |
| Sponsor | Helsinki University Central Hospital |
| Drug class | Sedative/Hypnotic combination |
| Modality | Small molecule |
| Therapeutic area | Neurology/Anesthesia |
| Phase | FDA-approved |
Mechanism of action
Sedative mixtures typically combine multiple CNS depressants (such as benzodiazepines, barbiturates, or other hypnotics) to achieve enhanced sedative effects through synergistic action on GABAergic and other inhibitory neurotransmitter pathways. The specific composition and mechanism depend on the individual components of the mixture formulated by Helsinki University Central Hospital.
Approved indications
- Sedation in clinical settings
- Anxiety management
Common side effects
- Drowsiness
- Respiratory depression
- Dependence potential
- Cognitive impairment
Key clinical trials
- Effects of Different Sedation Techniques on Early Cognitive Recovery After Ambulatory Gynecologic Surgery (NA)
- Efficacy Study of Dexmedetomidine Nasal Spray Combined With Propofol for Deep Sedation in ERCP (NA)
- Anxiolytic Effectiveness of Virtual Reality Glasses in Surgery (NA)
- "Comparison of the Effectiveness of Conventional Radiofrequency Thermocoagulation and Chemical Ablation With Phenol on Articular Branches of Femoral and Obturator Nerves in Chronic Hip Pain" (NA)
- The Application of Thoracic Epidural Analgesia in Patients With Acute Pancreatitis (NA)
- Intranasal Dexmedetomidine Sedation During Intra-articular Joint Injections in Pediatric Population (PHASE4)
- Quality of Recovery Following Opioids Free Anaesthesia in Laparoscopic Sleeve Gastrectomy (NA)
- DuoStim in Cases of PGT: Comparison of Embryo Quantity and Embryonic Quality Using MitoScore (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |