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secretin, biologically derived porcine
secretin, biologically derived porcine is a hormone Small molecule drug developed by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). It is currently in Phase 3 development for Treatment of pancreatic fistula.
Secretin is a hormone that stimulates the pancreas to release digestive enzymes and bicarbonate.
Secretin, a biologically derived porcine drug, has been evaluated in a Phase 3 trial for autism but lacks FDA approval. It is not commercially available and has no current revenue. The drug's mechanism involves regulating gastrointestinal functions, but its efficacy in autism remains inconclusive.
At a glance
| Generic name | secretin, biologically derived porcine |
|---|---|
| Sponsor | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) |
| Drug class | hormone |
| Target | secretin receptor |
| Modality | Small molecule |
| Therapeutic area | Gastroenterology |
| Phase | Phase 3 |
Mechanism of action
Secretin works by binding to secretin receptors on the surface of pancreatic acinar cells, which triggers a signaling cascade that leads to the release of digestive enzymes and bicarbonate into the small intestine. This helps to neutralize stomach acid and facilitate the digestion of nutrients.
Approved indications
- Treatment of pancreatic fistula
Common side effects
- Nausea
- Vomiting
- Diarrhea
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- secretin, biologically derived porcine CI brief — competitive landscape report
- secretin, biologically derived porcine updates RSS · CI watch RSS
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) portfolio CI
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Related
- Drug class: All hormone drugs
- Target: All drugs targeting secretin receptor
- Manufacturer: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) — full pipeline
- Therapeutic area: All drugs in Gastroenterology
- Indication: Drugs for Treatment of pancreatic fistula
- Compare: secretin, biologically derived porcine vs similar drugs
- Pricing: secretin, biologically derived porcine cost, discount & access