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Scopolamine Transdermal Patch [Transderm Scop]
Scopolamine acts as a muscarinic acetylcholine receptor antagonist, blocking the action of acetylcholine at muscarinic receptors in the central and peripheral nervous system.
Scopolamine acts as a muscarinic acetylcholine receptor antagonist, blocking the action of acetylcholine at muscarinic receptors in the central and peripheral nervous system. Used for Prevention of motion sickness, Treatment of postoperative nausea and vomiting.
At a glance
| Generic name | Scopolamine Transdermal Patch [Transderm Scop] |
|---|---|
| Also known as | TDS, Patch |
| Sponsor | Naval Aeromedical Research Unit, Dayton |
| Drug class | Anticholinergic |
| Target | Muscarinic acetylcholine receptors (M1-M5) |
| Modality | Small molecule |
| Therapeutic area | Motion Sickness, Postoperative Nausea and Vomiting |
| Phase | Phase 3 |
Mechanism of action
This blockade results in decreased parasympathetic activity, leading to reduced salivation, bronchial secretions, and gastrointestinal motility. Additionally, scopolamine's central effects can cause drowsiness, confusion, and amnesia.
Approved indications
- Prevention of motion sickness
- Treatment of postoperative nausea and vomiting
Common side effects
- Dry mouth
- Dizziness
- Headache
- Fatigue
- Confusion