Last reviewed 2026-04-19 · How we verify

Savella

At a glance

Approved indications

No approved indications tracked.

Boxed warnings

• WARNING: SUICIDALITY AND ANTIDEPRESSANT DRUGS SAVELLA is a selective serotonin and norepinephrine reuptake inhibitor (SNRI), similar to some drugs used for the treatment of depression and other psychiatric disorders. Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD) and other psychiatric disorders. Anyone considering the use of such drugs in a c

Common side effects

No common side effects on file.

Key clinical trials

• Comparison of Aripiprazole Augmentation vs Switching to Different Class of Antidepressants for Patients With MDD Who Are Partially/Minimally Responsive to Current Antidepressants:Randomized, Rater-bli (NA)
• A Phase III Pivotal, Multicenter, Double-Blind, Randomized, Placebo-Controlled Study of Milnacipran for the Treatment of Fibromyalgia (Phase 3)
• Effect of Foot Massage Performed to the Mother After Post-Bırth on Breastfeedıng Success, Sleep Qualıty and Neonatal Stress: a Randomızed Controlled Study (NA)
• Novel Medication as a Potential Smoking Cessation Aid (NA)
• A European Phase III, Multicentre, Double-blind, Randomised, Monotherapy, 12-month Study of Milnacipran for the Treatment of the Fibromyalgia Syndrome (Phase 3)
• A Multicenter, Randomized, Double-blind, Placebo-Controlled Discontinuation Study of the Durability of Effect of Milnacipran for the Treatment of Fibromyalgia in Patients Receiving Long-term Milnacipr (Phase 4)
• Effect of Peanut Ball Use ın Prımarıes on Labor Paın, Duratıon of Labor Anxıety and Maternal Satısfactıon (NA)
• Clemastine for Improving White Matter and Boosting Antidepressant Response in Late-life Depression (Phase 2)

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.