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Sampling synovial fluid
Sampling synovial fluid is a diagnostic procedure that collects fluid from the joint space to analyze cellular, chemical, and microbiological composition for disease diagnosis and monitoring.
Sampling synovial fluid is a diagnostic procedure that collects fluid from the joint space to analyze cellular, chemical, and microbiological composition for disease diagnosis and monitoring. Used for Diagnostic procedure for joint disorders including rheumatoid arthritis, gout, septic arthritis, and other inflammatory or infectious joint conditions.
At a glance
| Generic name | Sampling synovial fluid |
|---|---|
| Sponsor | Radboud University Medical Center |
| Modality | Small molecule |
| Therapeutic area | Rheumatology/Orthopedics |
| Phase | FDA-approved |
Mechanism of action
This is a clinical diagnostic technique rather than a pharmaceutical drug. It involves aspiration of synovial fluid from a joint cavity using a needle, allowing laboratory analysis of white blood cell counts, crystal identification, glucose levels, protein content, and microbial cultures. The procedure aids in diagnosing conditions such as rheumatoid arthritis, gout, septic arthritis, and other joint disorders.
Approved indications
- Diagnostic procedure for joint disorders including rheumatoid arthritis, gout, septic arthritis, and other inflammatory or infectious joint conditions
Common side effects
- Joint pain or discomfort
- Bleeding or hematoma at puncture site
- Infection
Key clinical trials
- Joint Endoprostheses Can Succesfully Treat Disabling Osteoarthritis. However, Infection is an Important Cause of Failure. Adequate Diagnostics Remains Challenging. Combining Advanced Imaging With Next-generation Sequencing of Samples Obtained Endoscopically Should Aid in Mapping and Characterizing. (NA)
- Evaluating Changes in Synovial Fluid Before and After GAE for Knee Osteoarthritis (NA)
- Identification of New Biomarkers to Promote Personalized Treatment of Patients With Inflammatory Rheumatic Diseases
- Immunopathology of Polymyalgia Rheumatica on Shoulder Bursae's Biopsies (NA)
- Thromboxane A2 and Osteoarthritis
- Periarticular Penetration of Cefazolin and Clindamycin in Second Stage Revision Arthroplasty of the Hip (PHASE4)
- Study of Systemic Impact of Trace Elements Release by Implantable Medical Devices. Identification of Biomarkers of Systemic Inflammation (NA)
- Tissue and Clinical Characterisation of Temporomandibular Joint Diseases
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Sampling synovial fluid CI brief — competitive landscape report
- Sampling synovial fluid updates RSS · CI watch RSS
- Radboud University Medical Center portfolio CI