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Salvage Therapy
Salvage therapy refers to treatment regimens administered to patients who have failed or become resistant to standard first-line cancer therapies.
Salvage therapy refers to treatment regimens administered to patients who have failed or become resistant to standard first-line cancer therapies. Used for Recurrent or refractory malignancies (specific indication depends on cancer type and prior treatment history).
At a glance
| Generic name | Salvage Therapy |
|---|---|
| Also known as | prostatectomy, Sofosbuvir,simeprevir, daclatasvir, ribavirin or sofosbuvir and querevo |
| Sponsor | H. Lee Moffitt Cancer Center and Research Institute |
| Modality | Small molecule |
| Therapeutic area | Oncology |
| Phase | FDA-approved |
Mechanism of action
Salvage therapy is not a single drug but rather a clinical approach using alternative chemotherapy agents, targeted therapies, or immunotherapies in patients with recurrent or refractory malignancies. The specific mechanism depends on the individual agents selected and the cancer type being treated. These regimens are designed to overcome resistance mechanisms that emerged during initial treatment.
Approved indications
- Recurrent or refractory malignancies (specific indication depends on cancer type and prior treatment history)
Common side effects
Key clinical trials
- Shared Decision-Making Decision Aid for Newly Diagnosed Breast Cancer : A Multi-Center Randomized Controlled Trial (NA)
- Project Tendura: The Impact of Blood Flow Restriction Resistance Training (BFR-RT) in Patients With Achilles Tendon Rupture (ATR) Repair (NA)
- ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors (PHASE1, PHASE2)
- Virotherapy and Natural History Study of KHSV-Associated Multricentric Castleman s Disease With Correlates of Disease Activity (PHASE2)
- National Study on the Epidemiology and Effectiveness of Therapies in the Treatment of Scabies
- A Brief Case Management Intervention to Promote Personal Recovery and Prevent Psychiatric Involuntary Readmissions: a Randomised Controlled Trial (NA)
- Serratus Plane Block (SPB) Versus Capsaïcine Versus Botox-A for Chronic Neuropathic Pain in Post-mastectomy Syndrome (PHASE2)
- Enhancing Prospective Thinking in Early Recovery (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Salvage Therapy CI brief — competitive landscape report
- Salvage Therapy updates RSS · CI watch RSS
- H. Lee Moffitt Cancer Center and Research Institute portfolio CI