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Saline Water (Control)
Saline water serves as an inert control comparator that provides no active pharmacological effect.
Saline water serves as an inert control comparator that provides no active pharmacological effect. Used for Control arm in clinical trials (non-therapeutic use).
At a glance
| Generic name | Saline Water (Control) |
|---|---|
| Also known as | Placebo |
| Sponsor | Rigshospitalet, Denmark |
| Modality | Small molecule |
| Phase | FDA-approved |
Mechanism of action
Saline water (typically 0.9% sodium chloride in water) is an isotonic solution used as a placebo or control arm in clinical trials. It has no active mechanism of action and is used to establish baseline efficacy and safety profiles of investigational drugs by comparison.
Approved indications
- Control arm in clinical trials (non-therapeutic use)
Common side effects
- Minimal adverse events expected; may include mild local irritation if injected
Key clinical trials
- Safety and Efficacy of Faricimab in Patients With NPDR (PHASE2)
- Evaluation of Sentinel Node Policy in Early Stage Endometrial Carcinomas at Intermediate and High Risk of Recurrence. (PHASE3)
- Effectiveness of Vitamin b12 Versus Kenalog on Traumatic Ulcer Associated With Orthodontic Treatment (NA)
- Hypertonic Saline Nasal Irrigation and Gargling in Suspected or Confirmed COVID-19 (ELVIS COVID-19) (NA)
- Add-on Intravenous Immunoglobulins in Early Myositis (PHASE2, PHASE3)
- Effects of the Adjunctive Use of Hyaluronic Acid-based Gel With Coranally Advanced Flap in the Gingival Recession (PHASE1, PHASE2)
- RECOVER-AUTONOMIC Platform Protocol (PHASE2)
- Effect of Graphene Oxide on Vital and Non-Vital Primary Teeth Compared to the Conventional Techniques (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Saline Water (Control) CI brief — competitive landscape report
- Saline Water (Control) updates RSS · CI watch RSS
- Rigshospitalet, Denmark portfolio CI