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Saline Solution (TA0)
Saline solution provides isotonic fluid replacement and electrolyte balance by delivering sodium chloride and water to maintain osmotic equilibrium.
Saline solution provides isotonic fluid replacement and electrolyte balance by delivering sodium chloride and water to maintain osmotic equilibrium. Used for Fluid and electrolyte replacement, Vehicle for intravenous drug delivery, Wound irrigation and topical cleansing.
At a glance
| Generic name | Saline Solution (TA0) |
|---|---|
| Sponsor | University Hospital, Lille |
| Modality | Small molecule |
| Therapeutic area | Supportive Care / Fluid Management |
| Phase | FDA-approved |
Mechanism of action
Normal saline (0.9% sodium chloride) is a physiologic solution that matches the osmolarity of blood plasma, allowing safe intravenous or topical administration without causing cell lysis or crenation. It serves as a basic vehicle for drug delivery, fluid resuscitation, and electrolyte maintenance in clinical settings. Saline has no active pharmacologic mechanism beyond osmotic and hydration effects.
Approved indications
- Fluid and electrolyte replacement
- Vehicle for intravenous drug delivery
- Wound irrigation and topical cleansing
Common side effects
- Hyperchloremic acidosis (with large volumes)
- Hypernatremia (with excessive administration)
- Fluid overload
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Saline Solution (TA0) CI brief — competitive landscape report
- Saline Solution (TA0) updates RSS · CI watch RSS
- University Hospital, Lille portfolio CI