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Saline Solution for Injection
Saline solution provides isotonic fluid replacement and electrolyte balance by delivering sodium chloride and water intravenously.
Saline solution provides isotonic fluid replacement and electrolyte balance by delivering sodium chloride and water intravenously. Used for Fluid and electrolyte replacement, Maintenance of intravascular volume, Vehicle for intravenous drug administration.
At a glance
| Generic name | Saline Solution for Injection |
|---|---|
| Also known as | Saline Solution, Normal Saline, Standard, Sodium Chloride 0.9%, NS |
| Sponsor | Charite University, Berlin, Germany |
| Modality | Small molecule |
| Therapeutic area | Supportive Care / Fluid & Electrolyte Management |
| Phase | FDA-approved |
Mechanism of action
Saline solution (0.9% sodium chloride) is an isotonic crystalloid fluid that maintains osmotic balance with blood plasma. It replaces intravascular volume, restores electrolytes (sodium and chloride), and supports perfusion and cellular function. It is used as a basic physiological support agent rather than a disease-modifying therapeutic.
Approved indications
- Fluid and electrolyte replacement
- Maintenance of intravascular volume
- Vehicle for intravenous drug administration
Common side effects
- Hyperchloremic acidosis (with large volumes)
- Fluid overload / pulmonary edema (in susceptible patients)
- Hypokalemia (with prolonged use)
Key clinical trials
- Endorotor Resection In Refractory Barrett's Dysplasia Patients (NA)
- Magnesium Supplementation in Advanced Non-small Cell Lung Cancer (NSCLC) (PHASE2, PHASE3)
- Tirzepatide in MetALD (PHASE2)
- FAP-targeted PET/NIR in Lung Malignant Tumors
- Thumb Base Osteoarthritis: Ultrasound-guided Platelet-rich Plasma Versus Placebo Injection (PHASE2)
- Safety Evaluation of PfSPZ Vaccine in Pregnant Women in Mali (MalVIP1) (PHASE1)
- SMILE Trial - Imaging Sub-Study
- Repeated Bilateral Greater Occipital Nerve Blockade in Chronic Migraine and Chronic Tension-Type Headache (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Saline Solution for Injection CI brief — competitive landscape report
- Saline Solution for Injection updates RSS · CI watch RSS
- Charite University, Berlin, Germany portfolio CI