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Saline-only catheter flush
Saline-only catheter flush maintains catheter patency and prevents thrombosis by delivering sterile normal saline through the catheter lumen without anticoagulant or antimicrobial additives.
Saline-only catheter flush maintains catheter patency and prevents thrombosis by delivering sterile normal saline through the catheter lumen without anticoagulant or antimicrobial additives. Used for Maintenance of central venous catheter patency, Peripheral intravenous catheter patency maintenance, Prevention of catheter-related thrombosis.
At a glance
| Generic name | Saline-only catheter flush |
|---|---|
| Also known as | Intervention group |
| Sponsor | TriHealth Inc. |
| Modality | Small molecule |
| Therapeutic area | Medical Device/Vascular Access |
| Phase | FDA-approved |
Mechanism of action
This is a mechanical/physical intervention rather than a pharmacological one. The saline solution flushes the catheter to remove blood, fibrin, and other debris that could occlude the line, maintaining vascular access. It relies on the flushing action and the physiological properties of isotonic saline to prevent clot formation and maintain catheter function.
Approved indications
- Maintenance of central venous catheter patency
- Peripheral intravenous catheter patency maintenance
- Prevention of catheter-related thrombosis
Common side effects
- Catheter occlusion
- Thrombophlebitis
- Catheter-related bloodstream infection
Key clinical trials
- PET/MRI for Evaluation of Endometriosis
- Monitoring Breast Cancer Immunotherapy Treatment With Advanced Positron Emission Tomography Magnetic Resonance Imaging (PET/MRI) (EARLY_PHASE1)
- Impact of Dynamic CoROnary RoADmap System for Guidance of Instantaneous Wave-Free Ratio or Fractional Flow Reserve (NA)
- First-in-Human Expanded Cohort Study of Intrapleural Administration of TolueneSulfonamide in Patients With Malignant Pleural Effusion (PHASE1, PHASE2)
- Autologous CAR-T Cells Targeting B7-H3 in Recurrent or Refractory GBM CAR.B7-H3Tc (PHASE1)
- Value of [68Ga]Ga-PSMA-11 PET/MRI in the Assessment of Liver Cirrhosis
- A Phase 2 Study of Methylene Blue Photodynamic Therapy for Treatment of Breast Abscesses (PHASE2)
- UROtainer for Bladder Catheter Maintenance, Infection Prevention and Quality of Life (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |