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Saline Nasal Mist
Saline nasal mist delivers sterile saltwater solution to the nasal passages to cleanse, moisturize, and relieve nasal congestion.
Saline nasal mist delivers sterile saltwater solution to the nasal passages to cleanse, moisturize, and relieve nasal congestion. Used for Nasal congestion relief, Nasal irrigation and cleansing, Sinus symptom management.
At a glance
| Generic name | Saline Nasal Mist |
|---|---|
| Also known as | Placebo |
| Sponsor | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's |
| Modality | Small molecule |
| Therapeutic area | Otolaryngology / Nasal Care |
| Phase | FDA-approved |
Mechanism of action
The hypertonic or isotonic saline solution works by osmotic action to reduce mucosal edema and clear nasal secretions and debris. It is a non-pharmacological, mechanical intervention that helps restore normal nasal airflow and mucociliary clearance without systemic absorption or receptor-mediated effects.
Approved indications
- Nasal congestion relief
- Nasal irrigation and cleansing
- Sinus symptom management
Common side effects
- Nasal irritation
- Mild stinging or burning
Key clinical trials
- Cromoglicate Adjunctive Therapy for Outpatients With Schizophrenia (PHASE1, PHASE2)
- The Importance of Insulin Action in the Brain for the Immune System During Physical Activity-Overweight (NA)
- Nasal Steroids, Irrigation, Oral Antibiotics, and Subgroup Targeting for Effective Management of Acute Sinusitis (PHASE4)
- Neural Mechanisms of Immersive Virtual Reality in Chronic Pain (PHASE1, PHASE2)
- Relative Contribution of Brain Insulin Action for Postprandial Metabolism (NA)
- Cooling to Alleviate Migraine #3 (NA)
- Safety and Efficacy of Human Adipose-Derived Stem Cell Exosomes in Acute Ischemic Stroke (PHASE1, PHASE2)
- Bacterial Composition and Immune Responses in the Nose and Oropharynx During Influenza Infection (PHASE1)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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