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saline intranasal
saline intranasal is a Nasal decongestant/irrigant Small molecule drug developed by Louisiana State University Health Sciences Center in New Orleans. It is currently FDA-approved for Nasal congestion relief, Nasal irrigation and cleansing, Allergic rhinitis symptom management.
Saline intranasal delivers sterile salt water solution directly into the nasal cavity to cleanse, moisturize, and relieve nasal congestion.
Saline intranasal delivers sterile salt water solution directly into the nasal cavity to cleanse, moisturize, and relieve nasal congestion. Used for Nasal congestion relief, Nasal irrigation and cleansing, Allergic rhinitis symptom management.
At a glance
| Generic name | saline intranasal |
|---|---|
| Sponsor | Louisiana State University Health Sciences Center in New Orleans |
| Drug class | Nasal decongestant/irrigant |
| Modality | Small molecule |
| Therapeutic area | Otolaryngology/Rhinology |
| Phase | FDA-approved |
Mechanism of action
Intranasal saline works through mechanical irrigation and osmotic effects, removing mucus, allergens, and irritants from the nasal passages while hydrating the nasal mucosa. The isotonic or hypertonic salt solution helps reduce inflammation and restore normal nasal function without pharmacological action on specific molecular targets.
Approved indications
- Nasal congestion relief
- Nasal irrigation and cleansing
- Allergic rhinitis symptom management
- Sinusitis adjunctive therapy
Common side effects
- Nasal irritation
- Epistaxis (minor)
- Throat irritation
Key clinical trials
- A Safety and Immunogenicity Trial of Boost-2867 Vaccine, Via Intranasal and Intramuscular Routes (PHASE1)
- Safety and Feasibility of Intranasal Insulin in Patients With Spinal Cord Injury (PHASE1)
- Directed Topical Drug Delivery for Treatment for PASC Hyposmia (PHASE2)
- Intranasal Dexmedetomidine-esketamine Administration and Postoperative Pain in Pediatric Patients (PHASE4)
- The Importance of Insulin Action in the Brain for the Immune System During Physical Activity-Overweight (NA)
- Evaluation of the Safety and Preliminary Efficacy of Neuroinduced Mesenchymal Stem Cells and Exosome Therapy in Patients With Spinocerebellar Palsy (PHASE1, PHASE2)
- Oxytocin to Treat PTSD (PHASE2)
- Nasal Steroids, Irrigation, Oral Antibiotics, and Subgroup Targeting for Effective Management of Acute Sinusitis (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- saline intranasal CI brief — competitive landscape report
- saline intranasal updates RSS · CI watch RSS
- Louisiana State University Health Sciences Center in New Orleans portfolio CI
Frequently asked questions about saline intranasal
What is saline intranasal?
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Related
- Drug class: All Nasal decongestant/irrigant drugs
- Manufacturer: Louisiana State University Health Sciences Center in New Orleans — full pipeline
- Therapeutic area: All drugs in Otolaryngology/Rhinology
- Indication: Drugs for Nasal congestion relief
- Indication: Drugs for Nasal irrigation and cleansing
- Indication: Drugs for Allergic rhinitis symptom management
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing