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Salbutamol (Ventolin®)
Salbutamol (Ventolin®) is a Short-acting beta-2 adrenergic agonist (SABA) Small molecule drug developed by Khyber Teaching Hospital. It is currently FDA-approved for Acute bronchospasm and reversible airway obstruction in asthma, Chronic obstructive pulmonary disease (COPD) with reversible airway obstruction, Prevention of exercise-induced bronchospasm. Also known as: Group A patients: Salbutamol (Ventolin®)., Albuterol.
Salbutamol is a beta-2 adrenergic agonist that binds to beta-2 receptors on airway smooth muscle, causing relaxation and bronchodilation.
Salbutamol (Ventolin) is used to treat conditions such as Chronic Obstructive Pulmonary Disease, Pulmonary Disease, Chronic Obstructive, Asthma, and Bronchial Asthma. Its mechanism of action involves bronchodilation, although the specific details of its mechanism are not provided in the given facts.
At a glance
| Generic name | Salbutamol (Ventolin®) |
|---|---|
| Also known as | Group A patients: Salbutamol (Ventolin®)., Albuterol |
| Sponsor | Khyber Teaching Hospital |
| Drug class | Short-acting beta-2 adrenergic agonist (SABA) |
| Target | Beta-2 adrenergic receptor (ADRB2) |
| Modality | Small molecule |
| Therapeutic area | Respiratory |
| Phase | FDA-approved |
Mechanism of action
Salbutamol activates beta-2 adrenergic receptors on bronchial smooth muscle cells, triggering a cascade that increases intracellular cAMP levels. This leads to smooth muscle relaxation and rapid airway dilation, relieving bronchoconstriction. It is a short-acting beta-2 agonist (SABA) used for acute relief of airway obstruction.
Approved indications
- Acute bronchospasm and reversible airway obstruction in asthma
- Chronic obstructive pulmonary disease (COPD) with reversible airway obstruction
- Prevention of exercise-induced bronchospasm
Common side effects
- Tremor (fine hand tremor)
- Headache
- Nervousness or anxiety
- Palpitations
- Muscle cramps
- Tachycardia
Key clinical trials
- Open-label Study to Assess Reduction of Background Asthma Medication While Sustaining Asthma Control and Clinical Remission With Tezepelumab in Patients 12-80yrs With Severe Asthma. (PHASE3)
- Clinical Assessment of Acupuncture for the Treatment of Chronic Asthma (NA)
- A Study to Evaluate the Efficacy and Safety of QVM149 (Indacaterol Acetate / Glycopyrronium Bromide / Mometasone Furoate) Versus Salmeterol Xinafoate/Fluticasone Propionate in Children From 12 Years to Less Than 18 Years of Age With Asthma. (PHASE3)
- Effect of Intraoperative Salbutamol Administration on Mechanical Power and Respiratory Mechanics in Obese Patients Undergoing Laparoscopic Bariatric Surgery (NA)
- Evaluation of the Effectiveness of the Nebulization Bronchodilators Under High Nasal Flow Humidified (NA)
- the Inhaled β2-adrenergic Receptor Agonist for Transient Tachypnoea of the Newborn (the REFSAL Trial) (PHASE3)
- Efficacy of Fluticasone Propionate Associated With Salmeterol Using Inhalation Chamber Versus Placebo to Improve the Respiratory Function in Children Over Six Years of Age Who Underwent Allogeneic Hematopoietic Stem Cell Transplantation With a Decline of FEV1 ≥10% From Pre Transplantation (PHASE3)
- A Study Evaluating the Effect of Inhaled PT007(AS MDI) Versus Placebo MDI and Ventolin Evohaler on Lung Function in Adult Participants With Asthma (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Salbutamol (Ventolin®) CI brief — competitive landscape report
- Salbutamol (Ventolin®) updates RSS · CI watch RSS
- Khyber Teaching Hospital portfolio CI
Frequently asked questions about Salbutamol (Ventolin®)
What is Salbutamol (Ventolin®)?
How does Salbutamol (Ventolin®) work?
What is Salbutamol (Ventolin®) used for?
Who makes Salbutamol (Ventolin®)?
Is Salbutamol (Ventolin®) also known as anything else?
What drug class is Salbutamol (Ventolin®) in?
What development phase is Salbutamol (Ventolin®) in?
What are the side effects of Salbutamol (Ventolin®)?
What does Salbutamol (Ventolin®) target?
Related
- Drug class: All Short-acting beta-2 adrenergic agonist (SABA) drugs
- Target: All drugs targeting Beta-2 adrenergic receptor (ADRB2)
- Manufacturer: Khyber Teaching Hospital — full pipeline
- Therapeutic area: All drugs in Respiratory
- Indication: Drugs for Acute bronchospasm and reversible airway obstruction in asthma
- Indication: Drugs for Chronic obstructive pulmonary disease (COPD) with reversible airway obstruction
- Indication: Drugs for Prevention of exercise-induced bronchospasm
- Also known as: Group A patients: Salbutamol (Ventolin®)., Albuterol
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing