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ROTAVAC 5C -F1

Bharat Biotech International Limited · Phase 3 active Biologic

ROTAVAC 5C-F1 is a live attenuated rotavirus vaccine that stimulates immune responses against rotavirus to prevent gastroenteritis.

ROTAVAC 5C-F1 is a live attenuated rotavirus vaccine that stimulates immune responses against rotavirus to prevent gastroenteritis. Used for Prevention of rotavirus gastroenteritis in infants and young children.

At a glance

Generic nameROTAVAC 5C -F1
SponsorBharat Biotech International Limited
Drug classLive attenuated rotavirus vaccine
ModalityBiologic
Therapeutic areaImmunology / Infectious Disease
PhasePhase 3

Mechanism of action

This is a pentavalent rotavirus vaccine candidate developed by Bharat Biotech containing five rotavirus strains (G1, G2, G3, G4, and G9). It works by introducing weakened rotavirus particles that trigger both humoral and mucosal immune responses, enabling the body to recognize and neutralize wild-type rotavirus before infection occurs. The vaccine is designed to provide broad protection against the most clinically relevant rotavirus genotypes.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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