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Ropivacaine 0.25% Injectable Solution
Ropivacaine is a local anesthetic that works by blocking nerve impulses, preventing pain.
Ropivacaine is a local anesthetic that works by blocking nerve impulses, preventing pain. Used for Postoperative pain management, Regional anesthesia.
At a glance
| Generic name | Ropivacaine 0.25% Injectable Solution |
|---|---|
| Sponsor | Rothman Institute Orthopaedics |
| Drug class | Local anesthetic |
| Target | Voltage-gated sodium channels |
| Modality | Small molecule |
| Therapeutic area | Anesthesiology |
| Phase | Phase 3 |
Mechanism of action
It does this by inhibiting the voltage-gated sodium channels in nerve cells, which are responsible for transmitting pain signals to the brain. This results in a temporary loss of sensation in the affected area.
Approved indications
- Postoperative pain management
- Regional anesthesia
Common side effects
- Nausea
- Dizziness
- Headache
- Tinnitus
- Seizure
Key clinical trials
- TAP Blocks With Ropivacaine Continuous Infusion Catheters vs Single Dose Liposomal Bupivicaine After Kidney Transplant (PHASE4)
- Intrathecal MoRphine Versus Transabdominal Plane Block (TAP) Block for AnalGesic Management in Elective Caesarean Section (PHASE4)
- A Multidisciplinary Perioperative Pain Management (NA)
- Exploring Long-term Pain Relief with 5% Dextrose Added to Local Anesthetic (NA)
- Comparing Effectiveness of CSE Versus DPE for Labor Analgesia (PHASE4)
- Fascia Iliaca Block for Postoperative Pain Control After Elective Hip Arthroplasty (NA)
- Evaluation of the Effectiveness of Two Methods of Regional Anesthesia During S-ICD Implantation Procedure. (NA)
- Femoral Nerve Block Versus Adductor Canal Nerve Block for Peri-Operative Analgesia Following Anterior Cruciate Ligament (ACL) Reconstruction: Evaluation of Post-operative Pain and Strength (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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