Last reviewed 2026-04-23 · How we verify

rocuronium continuous infusion maintenance

Rocuronium acts as a competitive antagonist at the nicotinic acetylcholine receptor, preventing acetylcholine from binding and thereby inhibiting muscle contraction.

Rocuronium acts as a competitive antagonist at the nicotinic acetylcholine receptor, preventing acetylcholine from binding and thereby inhibiting muscle contraction. Used for Endotracheal intubation and maintenance of muscle relaxation during surgery.

At a glance

Mechanism of action

This action results in muscle relaxation, which is useful for facilitating endotracheal intubation and maintaining muscle relaxation during surgery. Rocuronium's mechanism of action is similar to other non-depolarizing neuromuscular blockers.

Approved indications

• Endotracheal intubation and maintenance of muscle relaxation during surgery

Common side effects

• Hypotension
• Bradycardia
• Respiratory depression

Key clinical trials

• Comparison of Anesthetic Techniques for Early Recovery After Ankle Arthroscopy (NA)
• Opioid-Free vs Opioid-Based Anesthesia in Bariatric Surgery (NA)
• Continuous Versus 1-min Oscillometric Arterial BP Monitoring (NA)
• Inhalational Agents Versus Dexmedetomidine for Maintenance of General Anesthesia (NA)
• Intraoperative Multimodal Monitoring as a Means in Reducing the Duration of Mechanical Ventilation in High-Risk Patients Undergoing Major Abdominal Procedures - A Pilot Study (NA)
• Psychosocial Factors and Postoperative Pain in Aesthetic Breast Surgery
• LAPOFAR Trial: Opioid-Free vs. Remifentanil Anesthesia in Laparoscopic Cholecystectomy (NA)
• Effect of OFA, OSA Versus Opioid-based Anesthesia on NETs and Cancer Cell Malignancy After Colorectal Cancer Surgery (NA)

Primary sources

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