Last reviewed · How we verify
Exelon (rivastigmine)
At a glance
| Generic name | rivastigmine |
|---|---|
| Sponsor | Novartis |
| Target | Acetylcholinesterase, Cholinesterase, Acetylcholine receptor subunit epsilon |
| Therapeutic area | Neuroscience |
| Phase | FDA-approved |
Approved indications
- Alzheimer's disease
- Dementia associated with Parkinson's Disease
Common side effects
- Nausea
- Vomiting
- Diarrhea
- Anorexia
- Headache
- Dizziness
- Fatigue
- Asthenia
- Malaise
- Somnolence
- Increased Sweating
- Tremor
Key clinical trials
- Cholinergic Neurotransmission - A Common Underlying Mechanism of Cognitive and Gait Impairment in Parkinson Disease (Phase 4)
- A 24 Week, Multicenter, Open, Evaluation of the Clinical Effectiveness of the Once-daily 10 cm2 Rivastigmine Patch Formulation in Patients With Probable Alzheimer's Disease (MMSE 10-26) (Phase 4)
- Cholinesterase Inhibitors to Slow Progression of Visual Hallucinations in Parkinson's Disease:a Multi-center Placebo-controlled Trial. (Phase 4)
- Rivastigmine in the Treatment of Postoperative Delirium: a Pilot Clinical Trial (Phase 4)
- Randomized, 2-Way Crossover, Bioequivalence Study of Rivastigmine 1.5 mg Capsules and Exelon Administered as 1 x 1.5 mg Capsule in Healthy Subjects Under Fed Conditions (Phase 1)
- A 26-Week Open-Label Extension to Protocol No. CENA713BUS11: A 12-Week, Prospective, Double-blind, Placebo-controlled, Multi-center Study Evaluating the Efficacy and Safety of Rivastigmine 3 to 6 mg/D (Phase 4)
- A Double-Blind, Placebo-controlled Crossover Study to Assess the Pharmacokinetic Profile and the Physiological and Behavioral Effects of Repeat Rivastigmine (Exelon®) Administration in Young Healthy M (NA)
- Improved Language Acquisition Through Neuromodulation, Project Stage Ia (Phase 4)
Primary sources
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| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |