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Ringer-acetat
Ringer-acetat is a balanced crystalloid intravenous fluid that replaces electrolytes and fluid volume to maintain hemodynamic stability and acid-base balance.
Ringer-acetat is a balanced crystalloid intravenous fluid that replaces electrolytes and fluid volume to maintain hemodynamic stability and acid-base balance. Used for Hypovolemia and fluid replacement in perioperative and critical care settings, Maintenance of electrolyte balance and acid-base homeostasis.
At a glance
| Generic name | Ringer-acetat |
|---|---|
| Also known as | Ringer |
| Sponsor | Rigshospitalet, Denmark |
| Drug class | Crystalloid intravenous fluid |
| Modality | Small molecule |
| Therapeutic area | Critical Care / Fluid Resuscitation |
| Phase | FDA-approved |
Mechanism of action
Ringer-acetat (acetated Ringer's solution) is a physiologically balanced electrolyte solution containing sodium, potassium, calcium, chloride, and acetate. It is administered intravenously to restore intravascular volume, correct electrolyte imbalances, and maintain proper pH through the acetate buffer system, which is metabolized to bicarbonate in the liver.
Approved indications
- Hypovolemia and fluid replacement in perioperative and critical care settings
- Maintenance of electrolyte balance and acid-base homeostasis
Common side effects
- Hyperkalemia
- Hyperchloremic acidosis (less common than with normal saline)
- Fluid overload
- Hyponatremia
Key clinical trials
- Safety of Cell-free Adipose Tissue Product in Healthy Volunteers (NA)
- Albumin in Cardiac Surgery (PHASE4)
- Vasculopathic Injury and Plasma as Endothelial Rescue in Septic Shock Trial. VIPER-Sepsis (EudraCT no. 2016-000707-81) (PHASE4)
- Hemodynamic Effects of Cold Versus Warm Fluid Bolus (NA)
- Fluid Investigation Colloid vs Crystalloid Reg. Renal Hemodynamics and Function (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Ringer-acetat CI brief — competitive landscape report
- Ringer-acetat updates RSS · CI watch RSS
- Rigshospitalet, Denmark portfolio CI